Glycolithocholic Acid-3-Sulfate Analysis Service
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
- Liver Disease Research
- Biliary Disease Diagnosis
- Metabolic Disease Research
- Antiviral Drug Development
- Drug Metabolism Studies
Glycolithocholic acid-3-sulfate (GLCAS) is a bile acid derivative and a sulfated metabolite of cholic acid. This compound plays a pivotal role in bile secretion by enhancing bile acid solubility, thereby facilitating their excretion, which subsequently influences liver function and bile circulation. Research has indicated that GLCAS is associated not only with various hepatic and biliary diseases but also exhibits significant antiviral properties. Notably, GLCAS has been shown to protect MT-4 cells from HIV-1-induced cytopathic effects without exhibiting toxicity to host cells. Furthermore, GLCAS inhibits the expression of HIV-1 antigens in HIV-1 infected CEM cells. These findings underscore the potential clinical applications of GLCAS, particularly in the context of viral and hepatic diseases. Therefore, accurate detection and analysis of GLCAS are crucial for advancing our understanding of these diseases, developing therapeutic strategies, and monitoring treatment outcomes.
Figure 1. Molecular Structure of Glycolithocholic Acid-3-Sulfate
MtoZ Biolabs offers Glycolithocholic Acid-3-Sulfate Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in GLCA-3S detection.
Analysis Workflow
Service Advantages
Sample Submission Requirements
For detailed sample submission instructions, please consult our technical team.
Applications
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Glycolithocholic Acid-3-Sulfate
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into GLCA-3S's extensive physiological roles through top-tier analytical techniques and expert services.
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