Glycodeoxycholic Acid Analysis Service

Glycodeoxycholic acid (GDCA) is a conjugated bile acid, formed by the combination of glycine and deoxycholic acid, and is primarily found in the liver. GDCA plays a crucial role in bile acid metabolism, facilitating the digestion and absorption of fats, and is integral to the circulation and regulation of bile acids.

Figure 1. Molecular Structure of Glycodeoxycholic Acid

MtoZ Biolabs offers Glycodeoxycholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in GDCA detection.

Analysis Workflow

Service Advantages

1. High Sensitivity and Precision

HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of GDCA.

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

3. Wide Applicability

Suitable for various biological samples, including blood, urine, feces, and tissues.

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

Sample Submission Requirements

For detailed sample submission instructions, please consult our technical team.

Applications

• Facilitates the study of bile acid metabolic pathways and regulatory mechanisms.
• Monitoring GDCA levels can assist in diagnosing conditions such as cholestasis and cirrhosis.
• Evaluates the impact of drugs on bile acid metabolism, contributing to drug safety assessments.

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Glycodeoxycholic Acid

4. Raw Data

5. Custom Analysis Report

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into GDCA's extensive physiological roles through top-tier analytical techniques and expert services.