Gly-Ile Analysis Service
- The identification of novel disease biomarkers
- Improvement of disease diagnosis
- Acceleration of the discovery of novel therapeutics
- Discovery of new insights into disease mechanisms
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Gly-Ile consists of two amino acid residues: glycine and isoleucine. Glycine provides a simple hydrogen group, giving it high flexibility in the peptide chain, while isoleucine adds hydrophobicity and a branched structure. The molecular formula of Gly-Ile is C8H16N2O3, with a molecular weight of approximately 188.23 g/mol. Gly-Ile is a small peptide generated during protein degradation, and measuring its content can help evaluate protease activity, reflecting the digestive efficiency of the gastrointestinal tract in processing proteins. In patients with impaired digestive function, such as those with chronic pancreatitis or indigestion, detecting Gly-Ile levels can diagnose protease deficiency or functional decline. In the body, Gly-Ile is further metabolized into single amino acids or other metabolites by various enzymes. Analyzing the metabolites of Gly-Ile can further assess amino acid metabolism efficiency and conversion pathways, particularly in cases of branched-chain amino acid metabolism disorders or other amino acid-related pathological conditions.
Figure 1. The Structure of Gly-Ile
MtoZ Biolabs is pleased to introduce a top-tier Gly-Ile Analysis Service, supported by our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and highly skilled metabolomics team. Our service provides a thorough analysis of Gly-Ile, ensuring high sensitivity and accuracy.
Analysis Workflow
Service Advantages
1. High Sensitivity and Accuracy
MtoZ Biolabs' liquid chromatography-mass spectrometry (LC-MS) analysis platform can detect extremely low concentrations of Gly-Ile and its metabolites, which is particularly important for studying their minute changes in cells, tissues, and bodily fluids.
2. High Specificity
By optimizing chromatographic separation conditions and mass spectrometry detection parameters, Gly-Ile and its various metabolites can be effectively distinguished in complex biological samples, minimizing interference from other endogenous or exogenous substances and improving detection specificity.
3. Customized Analysis
Tailored analytical solutions can be designed according to research needs, providing personalized solutions for different biological samples and target molecules.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Gly-Ile
4. Raw Data
5. Custom Analysis Report
Through our Gly-Ile analysis service, we aim to facilitate your research and product development processes by providing accurate and reliable results. If you would like to inquire about our services, please feel free to contact us.
How to order?
