Glutaconic Acid Analysis Service

    Glutaconic acid is a naturally occurring unsaturated dicarboxylic acid, typically produced as an intermediate in the metabolism of amino acids such as lysine and tryptophan. Its molecular formula is C₅H₆O₄, with a molecular weight of 130.10 g/mol. Structurally, glutaconic acid contains a five-carbon chain with two carboxylic acid groups (-COOH) at each end and a trans double bond between the second and third carbons. This specific structure makes it an important compound in various biochemical pathways. Glutaconic Acid exhibits several biological activities and holds potential clinical applications in the development of metabolic supplements, diagnostic markers, and therapeutic agents. It is primarily known for its role as a biomarker in the diagnosis of specific metabolic disorders, such as glutaric aciduria type I and other organic acidemias. Furthermore, the analysis of glutaconic acid levels in biological samples can provide valuable insights into the functioning of mitochondrial metabolism and the regulation of energy production. As research progresses on its metabolic pathways and interactions, glutaconic acid could contribute to novel strategies for managing mitochondrial diseases, metabolic dysfunctions, and other related health conditions.

     

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    Figure 1. The structure of Glutaconic Acid

     

    MtoZ Biolabs utilizes our leading-edge LC-MS platform and a team of metabolomics experts to provide a comprehensive Glutaconic Acid Analysis Service. Our service ensures high sensitivity and accuracy in the analysis of glutaconic acid.

     

    Analysis Workflow 

     

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    Service Advantages

    1. Advanced Technological Platform

    We use industry-leading mass spectrometry equipment and analysis techniques to ensure high precision and reliability of the analysis results.

     

    2. Extensive Experimental Experience

    With years of experience in experimental operations and data processing, we can handle various complex biological samples.

     

    3. Rapid Data Delivery

    Ensure quick sample processing and timely delivery of research results to facilitate scientific progress.

     

    Applications

    • Qualitative and quantitative analysis of the glutaconic acid in various samples
    • Provide critical insights for metabolic pathway studies
    • Contribute to the development of diagnostic methods and targeted therapies

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. Each sample should have at least three replicates under the same condition. 

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Sample Preservation

    Store at -80°C to maintain stability.

     

    Note: Provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Glutaconic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    The Glutaconic Acid Analysis Service from MtoZ Biolabs is designed to provide you with accurate and reliable results, thus facilitating your research and product development processes.

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