Ginsenoside Analysis Service

    Ginsenosides are important active components found in Panax ginseng and belong to the class of triterpene saponins. The primary chemical structure types of ginsenosides are dammarane-type saponins, which are divided into 20(S)-protopanaxadiol types (such as ginsenoside Rb1, Rb2, Rc, Rd) and 20(S)-protopanaxatriol types (such as ginsenoside Re, Rg1, Rh1, Rf). These ginsenosides are considered the main source of ginseng's pharmacological effects and possess a variety of biological activities, including anti-inflammatory, anticancer, antioxidant, immunomodulatory, neuroprotective, and anti-aging effects. 

     

    The metabolism of ginsenoside is complex and primarily occurs in the intestines, where they are broken down by gut microbiota into secondary ginsenosides and other metabolites, which often exhibit stronger biological activities. Liquid chromatography-mass spectrometry (LC-MS) is commonly used for analyzing ginsenosides and their metabolites. This technique offers high sensitivity and high selectivity, making it suitable for analyzing ginsenosides in complex samples.

     

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    Figure 1. The Structure of Ginsenoside Rg1

     

    With an expert team of metabolomics researchers and state-of-the-art high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) platform, MtoZ Biolabs offers a sophisticated Ginsenoside Analysis Service. This service ensures high levels of sensitivity and accuracy in the comprehensive analysis of ginsenoside.

     

    Analysis Workflow

     

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    Service Advantages

    1. High cost-effectiveness. MtoZ Biolabs caters to clients seeking third-party testing services, offering a one-stop service model that significantly saves time. Our comprehensive project analysis solutions also ensure optimal cost-effectiveness.

     

    2. Exceptional analytical capabilities. With extensive experience in HPLC services, MtoZ Biolabs can swiftly and accurately interpret HPLC results, delivering expert analyses.

     

    3. Continuously advancing. Our fully-equipped laboratory network and professional technicians provide dependable plant targeted metabolomics services, along with real-time updates on industry knowledge.

     

    Applications

    • Qualitative analysis of ginsenoside metabolites
    • Quantitative analysis of ginsenoside content
    • Safety and quality assurance
    • Basis for continuous improvement

     

    Sample Submission Requirements

    1. Sample Types

    • Serum, plasma, urine, tissue samples, food, drugs
    • At least three same-condition materials must be selected for each sample

     

    2. Sample Volume

    • Minimum 200 µL of liquid sample
    • Minimum 200 mg of animal tissues
    • Minimum 1 g of plant tissues

     

    3. Sample Preservation

    Samples must be stored at -80°C to maintain stability

     

    Note: Details on sample collection and handling must be provided.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Ginsenoside

    4. Raw Data

    5. Custom Analysis Report

     

    Our ginsenoside analysis service is designed to support your research and product development endeavours by providing accurate and reliable results.

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