FBP Analysis Service

Fructose-1,6-bisphosphate (FBP) is a key metabolic intermediate involved in glycolysis and gluconeogenesis, serving as a critical regulator of energy metabolism in cells. In the glycolytic pathway, FBP is produced from fructose-6-phosphate by the action of phosphofructokinase-1 (PFK-1), a rate-limiting enzyme in the pathway, while in gluconeogenesis, FBP is dephosphorylated by fructose-1,6-bisphosphatase to regenerate fructose-6-phosphate. FBP plays a central role in regulating glucose metabolism and energy production. Its levels fluctuate in response to cellular energy demands, making it a critical target for studying metabolic health, insulin resistance, and other disorders such as diabetes and cancer. Recent research highlights FBP as a key player in cancer cell metabolism, where altered FBP levels can impact tumor growth and survival. Additionally, studies in metabolic engineering have demonstrated that manipulating FBP levels can enhance the production of biofuels and bioproducts in microorganisms.

 

Understanding the dynamics of FBP in both normal and pathological conditions is essential for uncovering the underlying mechanisms of metabolic diseases and optimizing metabolic pathways for industrial applications. Accurate quantification of FBP is therefore vital for metabolic research, providing insights into cellular energy status and pathway regulation.

 



 

Figure 1. The Structure of FBP

 

MtoZ Biolabs offers a comprehensive FBP analysis service using advanced mass spectrometry techniques. Our service is designed to overcome the challenges in FBP analysis, such as sensitivity and specificity issues, and provide accurate and reliable data.

 

Analysis Workflow

 



 

Service Advantages

1. Advance Analysis Platform

MtoZ Biolabs established an advanced FBP analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.

 

2. One-Time-Charge

Our pricing is transparent, no hidden fees or additional costs.

 

3. High-Data-Quality

Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all FBP analysis service data providing clients with a comprehensive data report.

 

4. Fast Turnaround

The process from sample handling to report generation is efficient, shortening the analysis cycle.

 

Applications

Our FBP analysis service can assist researchers in a variety of fields, including but not limited to:

• Drug development
• Disease diagnosis and prognosis
• Metabolic pathway analysis

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

 

Note: Please provide details on sample collection and handling.

 

Deliverables

1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on FBP

4. Raw Data

5. Custom Analysis Report

 

Join hands with MtoZ Biolabs to explore the hidden aspects of FBP and unleash the power of metabolic studies.