Estrone Analysis Service

    Estrone (E1), also spelled oestrone, is a crucial estrogen in the human body, predominantly produced by the ovaries, adrenal glands, and peripheral tissues. As a key steroid hormone, E1 significantly influences female physiological functions, including menstrual cycle regulation, reproductive tissue health maintenance, bone density balance, and cardiovascular support. In postmenopausal women, E1 becomes the principal circulating estrogen, compensating for diminished ovarian function.

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    Figure 1. Molecular Structure of Estrone

     

    Maintaining normal E1 levels is essential for female health. Deviations in E1 levels can lead to various health issues such as menstrual irregularities, infertility, osteoporosis, cardiovascular diseases, and specific cancers like breast and endometrial cancer. Furthermore, abnormal E1 levels are linked to endocrine disorders and metabolic syndrome. Accurate E1 measurement is vital for diagnosing these conditions, evaluating hormone treatment efficacy and safety, and gaining a comprehensive understanding of overall health.

     

    Recent research underscores the importance of E1 level monitoring in preventing and managing age-related conditions such as osteoporosis and cardiovascular diseases. In clinical settings, E1 measurements provide valuable insights into hormone balance, aiding physicians in formulating personalized treatment strategies.

     

    MtoZ Biolabs offers Estrone Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in E1 detection.

     

    Analysis Workflow

     

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    Service Advantages

    • Rapid Analysis Cycle and Cost-Effectiveness
    • Stable, Reliable, and Highly Sensitive Results
    • Comprehensive One-Stop Service for Extensive Testing Needs
    • User-Friendly Operation with Wide Application Scope
    • Supported by Extensive Bioanalytical Resources and Advanced Platforms

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissue extracts, and other biological samples.

     

    2. Sample Volume

    At least 200 μL of liquid sample or 200 mg of solid sample.

     

    3. Sample Preservation

    Store samples at -20°C or lower to prevent degradation, avoiding repeated freeze-thaw cycles.

     

    Note: Provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Estrone

    4. Raw Data

    5. Custom Analysis Report

     

    Our Estrone Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.

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