Desmosterol Analysis Service

    Desmosterol is a sterol compound with a chemical structure that includes four interconnected rings and a double bond between carbon positions 24 and 25. It is primarily formed as an intermediate in the cholesterol biosynthetic pathway, especially in the liver and other tissues. Desmosterol plays a structural role in cell membranes, enhancing membrane fluidity, and serves as a precursor for steroid hormones and vitamin D. Its metabolism mainly occurs in the liver, producing cholesterol and other metabolites. The metabolites of desmosterol exhibit significant biological activity in regulating lipid metabolism, cell proliferation, and immune responses. Research on desmosterol and its metabolites is crucial for understanding the mechanisms of steroid metabolism, cardiovascular diseases, and metabolic disorders, aiding in the identification of potential biomarkers and therapeutic targets.

     

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    Figure 1. The Structure of Desmosterol

     

    MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, providing advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. We employs a sophisticated LC-MS-based metabolomics platform for the analysis of desmosterol, which can ensure the accuracy of the quantification of desmosterol and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you have an interest in our desmosterol analysis service, don't hesitate to contact us. We are fully dedicated to providing you with top-notch analytical services and technical support.

     

    Analysis Workflow

    Our desmosterol analysis service includes extraction, preparation, and analysis of the samples. The process begins with a sample preparation, where the desmosterol is extracted from the samples. The extracted metabolites are then analyzed using our LC-MS-based metabolomics platform.

     

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    Service Advantages

    Our desmosterol analysis service offers several advantages including high sensitivity, high throughput, and a wide dynamic range. We provide accurate and reproducible results using our advanced LC-MS analysis techniques. The service also offers comprehensive data analysis and interpretation, helping to streamline your research and product development processes.

     

    Applications

    Our desmosterol analysis service can be applied in various fields including pharmaceutical research, clinical diagnostics, food safety, environmental testing, and more.

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. A minimum of three samples under the same conditions is necessary for each analysis.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Sample Preservation

    Samples should be stored at -80°C to maintain stability.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Desmosterol

    4. Raw Data

    5. Custom Analysis Report

     

    Our desmosterol analysis service aims to provide reliable and accurate results to support your research and product development. Please feel free to contact us for more information about our services.

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