Deoxycholic Acid Analysis Service

Deoxycholic acid (DCA) is a secondary bile acid produced through the conversion of primary bile acids by intestinal microbiota. It plays a vital role in lipid metabolism, cholesterol regulation, and the absorption of fat-soluble vitamins, making it essential for normal digestive functions. Elevated DCA levels are closely linked to gastrointestinal and liver diseases, including gallstones, non-alcoholic fatty liver disease, cirrhosis, and colorectal cancer, suggesting that DCA significantly influences the development and progression of these conditions.

 

DCA analysis is critical not only for understanding disease mechanisms but also has broad applications in drug development, nutrition science, and gut microbiome research. Accurate measurement of DCA concentrations and its metabolic profile provides researchers with valuable insights into its role in pathological processes, supporting clinical diagnosis and therapeutic strategy development.

 

Figure 1. Molecular Structure of Deoxycholic Acid

 

MtoZ Biolabs offers Deoxycholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in DCA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

Detects very low concentrations of DCA accurately.

 

2. High Specificity

Differentiates DCA from other compounds using mass spectrometry.

 

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

 

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

 

5. Versatility

Capable of analyzing DCA and its related metabolites.

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, feces, tissue extracts, and other biological samples.

 

2. Sample Volume

At least 200 μL of liquid sample or 200 mg of solid sample.

 

3. Sample Preservation

Store at -80°C to maintain stability.

 

Note: Provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Deoxycholic Acid

4. Raw Data

5. Custom Analysis Report

 

Our Deoxycholic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.