Dehydroisoandrosterone Analysis Service
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
Dehydroisoandrosterone (DHEA), also known as androstenolone, is a crucial endogenous steroid hormone precursor with various physiological roles. As one of the most abundant circulating steroids in humans, DHEA is produced by the adrenal glands, gonads, and brain. It functions as a precursor for both androgens and estrogens, playing a vital role in the biosynthesis of these hormones across different tissues. Beyond its role in hormone synthesis, DHEA exhibits distinct biological effects by interacting with multiple nuclear and cell surface receptors, serving as a neurosteroid and modulator of neurotrophic factor receptors.
Although DHEA itself is a relatively weak androgen, it can be converted into more potent androgens, such as testosterone and dihydrotestosterone (DHT), within the body. These androgens significantly influence hair growth and sebum production in the skin and hair follicles. During puberty, DHEA, along with other adrenal androgens, contributes to the development of secondary sexual characteristics, including early growth of pubic and axillary hair, adult-type body odor, increased oiliness of the skin and hair, and mild acne. Women with complete androgen insensitivity syndrome (CAIS), who have non-functional androgen receptors, show sparse or absent body hair, emphasizing the critical role of DHEA and other androgens in hair development.
Given the link between DHEA level fluctuations and various diseases such as osteoporosis, cardiovascular conditions, and cognitive impairments, precise measurement of DHEA is essential for understanding its impact on health and disease. Additionally, DHEA supplementation is commonly used in health and anti-aging treatments, further increasing the need for accurate detection of its levels.
Figure 1. Molecular Structure of Dehydroisoandrosterone
MtoZ Biolabs offers Dehydroisoandrosterone Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in DHEA detection.
Analysis Workflow
Service Advantages
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, saliva, and other biological samples.
2. Sample Volume
At least 200 μL of liquid sample or 200 mg of solid sample.
3. Sample Preservation
Store samples at -20°C or lower to prevent degradation, avoiding repeated freeze-thaw cycles.
Note: Provide details on sample collection and handling.
Applications
1. Hormone Level Research: Examine DHEA level variations to elucidate its role in health and disease.
2. Aging Research: Investigate the relationship between DHEA levels and age-related conditions, aiding anti-aging studies.
3. Endocrine Research: Explore DHEA’s role in the endocrine system and its potential as a therapeutic target.
4. Health Management: Monitor DHEA levels to guide personalized health and treatment strategies.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Dehydroisoandrosterone
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into DHEA's extensive physiological roles through top-tier analytical techniques and expert services.
How to order?
