Custom Peptide Synthesis Services

Synthesized peptides are essential tools in biological research, crucial for studying protein structures, functions, and interactions. Synthesized peptides play a vital role not only in basic research by elucidating mechanisms such as cell signaling, enzyme activity, and immune responses, but also in drug development, vaccine research, and clinical diagnostics. By synthesizing peptides with specific amino acid sequences and modifications, scientists can deeply explore the molecular mechanisms of diseases and provide a solid foundation for the development of innovative drugs and therapeutic approaches.

 

Services at MtoZ Biolabs

MtoZ Biolabs offers high-quality Custom Peptide Synthesis Services to meet the diverse needs of scientific research and biopharmaceutical fields. We provide a variety of peptide synthesis service, including:

1. Functional Peptides: Hormonal peptides, neuropeptides, antimicrobial peptides.

2. Antigen Peptides: Used in vaccine development, immunology research, and antibody screening, including tumor antigen peptides, pathogen epitope peptides, etc.

3. Modified Peptides: Such as phosphorylated peptides, acetylated peptides, glycosylated peptides, suitable for protein signaling, gene expression regulation, and other research.

4. Linear Peptides: Widely used in protein function studies, vaccine development, and antibody screening.

5. Cyclic Peptides: Used in drug development and targeted therapy, with enhanced stability and biological activity, commonly used in cancer immunotherapy and targeted molecular research.

6. Peptide Libraries: Used for screening specific protein-binding peptides or studying protein interactions, antibody specificity, and other biological questions.

 

Service Workflow

 



 

Service Advantages

1. Personalized Customization

We understand that every customer’s needs are unique, so we provide a tailored Custom Peptide Synthesis Services. Whether it is short peptides, long peptides, linear peptides, or cyclic peptides, we can synthesize peptides that meet the specific requirements of our clients. We support various amino acid modifications, such as phosphorylation, acetylation, glycosylation, etc., and allow clients to customize peptide length, sequence, and modifications based on research needs. Through flexible customization, we ensure that the peptides we deliver perfectly meet your experimental requirements.

 

2. Efficient Synthesis

MtoZ Biolabs employs industry-leading solid-phase peptide synthesis (SPPS) and liquid-phase peptide synthesis (LPPS) technologies, ensuring each synthesis step is efficient and precise. We use automated synthesis equipment to efficiently synthesize peptides based on client needs, with adjustable synthesis conditions tailored to different tasks. Through these advanced technologies, MtoZ Biolabs guarantees the efficiency and consistency of the synthesis process while ensuring the integrity of the peptide chain.

 

3. Strict Quality Control

We implement rigorous quality control for every batch of synthesized peptides to ensure high purity and biological activity. Each peptide undergoes high-performance liquid chromatography (HPLC) for purity testing, ensuring a purity level of over 90%. For peptides requiring higher purity, we conduct further purification. Additionally, we use mass spectrometry (MS) to confirm the peptide’s molecular weight and structure, ensuring its accuracy. For functional peptides, we perform biological activity validation to ensure the peptide’s effectiveness in practical applications. For example, for peptides used in vaccine development or immunology research, we conduct cell experiments or receptor binding tests to confirm their biological activity aligns with expectations.

 

4. Application Support

In addition to high-quality peptide synthesis, MtoZ Biolabs provides comprehensive application support to help clients better utilize custom peptides in research or commercialization projects. We offer functional validation, purity analysis, and technical support for relevant applications. Whether designing experimental plans, optimizing experimental conditions, or analyzing existing data, our expert team will provide in-depth consultation services. We assist clients in overcoming various technical issues encountered during peptide usage, such as enhancing experimental sensitivity and specificity, analyzing peptide stability under specific conditions, etc. With MtoZ Biolabs’ support, you can conduct experiments more efficiently and reduce potential technical challenges in the process.

 

Applications

1. Basic Research and Protein Function Analysis

Synthetic peptides are widely used to study protein structures, functions, and their interactions within cells. By providing precise peptide sequences and modifications, scientists can explore the effects of post-translational modifications (e.g., phosphorylation, acetylation) on protein function and investigate cellular signaling, metabolic regulation, and other processes.

 

2. Vaccine Development and Immunology Research

In vaccine research and development, synthetic antigen peptides are essential for studying vaccine immunogenicity and antibody production. By synthesizing antigen epitope peptides from specific pathogens, they can mimic viral, bacterial, or tumor cell antigens, thereby facilitating the design and optimization of vaccines.

 

3. Drug Screening and Targeted Therapy

Synthetic peptides play a key role in drug discovery, particularly when screening small molecule drugs for their interactions with target proteins. Custom peptides can serve as drug targets or ligands, helping scientists verify drug specificity and effectiveness and promoting the development of novel therapeutics.

 

4. Antibody Development and Epitope Recognition

By synthesizing antigen peptides with specific amino acid sequences, researchers can identify and validate antibody binding epitopes. Custom peptides expedite the screening of monoclonal antibodies, supporting efficient antibody development and optimization.

 

5. Clinical Diagnosis and Biomarker Research

Synthetic peptides are used in clinical diagnostics to develop new biomarkers. For instance, synthetic peptides can be used to detect specific disease markers, enabling early disease detection and monitoring through blood or other biological sample analysis.

 

Deliverables

1. Synthesized Peptide Product

Peptides synthesized according to the client’s specifications, including the designated amino acid sequence, length, and modifications. Reports will include information on peptide solubility, stability, and storage conditions to ensure optimal use.

 

2. Purity Analysis Report

Each batch of synthesized peptides undergoes HPLC analysis to ensure the purity meets client requirements. We provide a detailed purity report to ensure each peptide’s quality meets standards.

 

3. Mass Spectrometry Analysis Report

We provide MS analysis reports to verify the peptide’s molecular weight and structure, ensuring its correctness. The report includes molecular weight determination, structure confirmation, and other key information.

 

4. Functional Validation Data (if applicable)

For functional peptides, we provide biological activity validation data as needed. For instance, for antigen peptides used in vaccine development, we provide immunological response results; for drug screening peptides, we provide binding data with targets.

 

By choosing MtoZ Biolabs for your custom peptide synthesis needs, you will receive high-quality, tailor-made peptides to support your research, drug development, and clinical applications.

 

Contact us to discuss your peptide synthesis needs and get your personalized synthesis plan.