Calcitriol Analysis Service
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Calcitriol (1,25-dihydroxyvitamin D3) is the active form of vitamin D, primarily converted by the enzyme 1α-hydroxylase (CYP27B1) in the kidneys. Its chemical structure is 1α,25-dihydroxycholesterol, with the molecular formula C₂₇H₄₄O₃. The synthesis process involves two main stages: first, vitamin D3 (cholecalciferol) is converted in the liver to 25-hydroxyvitamin D3 (25(OH)D3), and then it is transformed into calcitriol in the kidneys by 1α-hydroxylase. Monitoring calcitriol levels helps assess the vitamin D status, avoiding vitamin D deficiency or excess. Vitamin D supplementation therapy often requires adjustment based on calcitriol levels to ensure therapeutic efficacy and safety. For patients receiving calcitriol treatment, monitoring calcitriol and its metabolites can help evaluate treatment effectiveness and make necessary adjustments.
Figure 1. The Structure of Calcitriol
MtoZ Biolabs offers an advanced Calcitriol Analysis Service, utilizing our sophisticated liquid chromatography-mass spectrometry (LC-MS) platform and experienced metabolomics team. Our service ensures a comprehensive calcitriol analysis with high sensitivity and exceptional accuracy.
Analysis Workflow
Service Advantages
Applications
1. Discovering new disease biomarkers
2. Enhancing disease diagnosis
3. Speeding up the discovery of innovative therapeutics
4. Uncovering new insights into disease mechanisms
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. For each sample, more than 3 materials under the same condition should be selected.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Calcitriol
4. Raw Data
5. Custom Analysis Report
Our Calcitriol Analysis Service is designed to facilitate your research and product development by delivering accurate, reliable results. Through this service, we aim to provide a comprehensive understanding of calcitriol, its origin, pharmacological action, and the technical principles of its analysis. We pride ourselves on our service advantages, which include a team of skilled professionals, state-of-the-art facilities, and a commitment to delivering reliable, accurate results.
How to order?
