Caffeine Analysis Service
- Qualitative analysis of the metabolites of caffeine
- Quantitative analysis of caffeine content
- Provide basis for drug development or food safety checks
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Caffeine, also known as 1,3,7-trimethylxanthine, is a naturally occurring methylxanthine alkaloid synthesized through the purine metabolism pathway in plants. Its structure consists of a xanthine core with three methyl groups attached to the nitrogen atoms at positions 1, 3, and 7. Caffeine has notable stimulant effects on the central nervous system, acting primarily as an adenosine receptor antagonist to block the sedative effects of adenosine, thereby enhancing neuronal activity and alertness.
Under various physiological and pathological conditions, changes in the levels and metabolic processes of caffeine are closely related to the occurrence and development of neurological disorders, cardiovascular diseases, and metabolic syndromes. Elevated levels of caffeine and its metabolites are frequently observed in the treatment of certain clinical symptoms such as headaches, migraines, and apnea. Therefore, measuring the levels of caffeine and its metabolites can serve as biomarkers for neural activity status and therapeutic efficacy. Additionally, since caffeine metabolism is closely linked to genetic polymorphisms, individual differences in response to caffeine may be used to assess potential risks in drug metabolism and personalized treatment. Monitoring caffeine metabolites helps evaluate its impact on the central nervous system and the pathophysiological states associated with neurological and metabolic diseases.
Figure 1. The Structure of Caffeine
At MtoZ Biolabs, we offer an outstanding Caffeine Analysis Service supported by our sophisticated liquid chromatography-mass spectrometry (LC-MS) platform and skilled metabolomics team. Our service yields a thorough caffeine analysis, delivering high sensitivity and precision.
Analysis Workflow
Service Advantages
1. Continuously refined protocols and cutting-edge analytical tools
2. Expert experimental planning
3. Rapid processing times
4. Exceptional precision, selectivity, and sensitivity
Applications
Sample Submission Requirements
1. Sample Types
We accept a variety of biological samples, including serum, plasma, urine, and tissues. For each sample, please provide more than 3 materials under identical conditions.
2. Sample Volume
3. Sample Preservation
To maintain stability, samples should be stored at -80°C.
Note: Please offer details about sample collection and handling procedures.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. In-depth Information on Caffeine
4. Raw Data
5. Custom Analysis Report
Our Caffeine Analysis Service is designed to support your research and product development efforts by providing accurate and dependable results.
How to order?
