β-Hyodeoxycholic Acid Analysis Service

    β-Hyodeoxycholic acid (β-HDCA), also referred to as isohyodeoxycholic acid, is a secondary bile acid primarily produced in the liver and through gut microbiota metabolism. Distinct from other bile acids, β-HDCA features a unique chemical structure and biological function, closely associated with various hepatobiliary and metabolic diseases. It plays a critical role in lipid metabolism, cholesterol regulation, and maintaining gut health. Abnormal levels of β-HDCA can indicate disease states or metabolic disorders. Accurate analysis of β-HDCA is essential for understanding its role in physiological and pathological conditions, offering valuable insights for disease diagnosis and treatment.

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    Figure 1. Molecular Structure of β-Hyodeoxycholic Acid

     

    MtoZ Biolabs offers β-Hyodeoxycholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in β-HDCA detection.

     

    Analysis Workflow

     

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    Service Advantages

    • Rapid Analysis Cycle and Cost-Effectiveness
    • Stable, Reliable, and Highly Sensitive Results
    • Comprehensive One-Stop Service for Extensive Testing Needs
    • User-Friendly Operation with Wide Application Scope
    • Supported by Extensive Bioanalytical Resources and Advanced Platforms

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, feces, tissue extracts, and other biological samples.

     

    2. Sample Volume

    At least 200 μL of liquid sample or 200 mg of solid sample.

     

    3. Sample Preservation

    Store at -80°C to maintain stability.

     

    Note: Provide details on sample collection and handling.

     

    Applications

    1. Bile Acid Metabolism Research: Explore the role of β-HDCA in bile acid metabolism, investigating its unique functions within the bile acid cycle.

     

    2. Gut Microbiota Research: Study the production and regulation of β-HDCA within the gut microbiota and its potential implications for gut health and disease.

     

    3. Metabolic Disease Research: Investigate the role of β-HDCA in metabolic diseases, particularly in lipid metabolism and cholesterol regulation.

     

    4. Disease Biomarker Research: Evaluate β-HDCA as a potential biomarker by assessing its level changes under different disease conditions.

     

    5. Drug Development: Analyze the metabolic pathways of β-HDCA to support the development of bile acid-related therapeutics.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on β-Hyodeoxycholic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    Our β-Hyodeoxycholic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.

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