Atopic Dermatitis Analysis Service

    Atopic dermatitis (AD) is prevalent among children aged 1 to 5 years and a considerable number of patients carry this condition into adulthood. As a chronic inflammatory skin disease, AD often coexists with asthma and rhinitis. At the cellular level, the hallmark of AD is characterized by high serum IgE levels, where T cells play a crucial regulatory role. Most T cells around the AD-affected tissue produce Th2 cell cytokines such as IL-4, IL-5, and IL-13, which are pathogenic factors. IL-4 and IL-13 secreted by T cells and mast cells can induce elevated levels of IgG and IgE.

     

    1798656093319118848-1790615719802671104-20221219-7301-AtopicDermatitis.jpg

    Biedermann, T. et al. Front Immunol. 2015.

    Figure 1. Atopic Dermatitis – Flow Cytometry Cytokine Detection

     

    MtoZ Biolabs utilizes flow cytometry to simultaneously quantify cytokines and proteins related to atopic dermatitis, providing higher sensitivity and a broader detection range.

     

    Atopic Dermatitis – Flow Cytometry Cytokine Detection Indicators

     

     

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    Figure 2. Atopic Dermatitis – Human Sample Single-factor Flow Cytometry Kit

     

    Sample Submission Requirements

    1. Only 25 µL of sample required, while traditional ELISA requires 50 µL or 100 µL samples.

    2. Suitable for serum, plasma, cell culture supernatant, and various body fluids.

    3. Body fluid samples are stored at -80°C and transported using dry ice. 

     

    Deliverables

    1. Experimental Procedures

    2. Raw Data

    3. Technical Report

    4. Result of Absolute Content of Each Detection Indicator (Excel Spreadsheet)

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