Amino Acid Profile Analysis Service

Amino acid profile analysis is an advanced quantitative technique used to determine the types and concentrations of amino acids in a sample. This technology is essential for understanding protein composition, function, and their roles in biological processes. Whether in basic research, drug development, food science, or clinical diagnostics, amino acid profile analysis provides critical data that supports researchers, pharmaceutical companies, and food industry professionals in optimizing product quality and refining research directions.

 

MtoZ Biolabs offers high-quality Amino Acid Profile Analysis Service using state-of-the-art analytical platforms and professional teams, ensuring data accuracy and reliability. We are committed to providing precise amino acid profiling to meet the research and industry needs across various fields, advancing scientific exploration and technological innovation.

 

Services at MtoZ Biolabs

Our Amino Acid Profile Analysis Service employ advanced technologies, including High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS), to accurately determine amino acid composition and concentration in samples. Whether analyzing individual amino acids or profiling amino acids in complex protein samples, we provide efficient and reliable solutions. Our services primarily address the following needs:

1. Protein Sequence Validation: By quantitatively analyzing amino acid composition, we verify whether the protein sequence aligns with expectations, helping researchers eliminate experimental errors.

2. Protein Purity Assessment: For large-scale protein production, amino acid profile analysis can accurately evaluate purity, ensuring the quality of the target protein.

3. Detection of Amino Acid Variations or Imbalances in Samples: During protein synthesis and purification, amino acid variations or imbalances can impact research outcomes or product functionality. amino acid profile analysis helps identify these issues and offers solutions.

4. Quantitative Analysis and Quality Control: For biopharmaceuticals, nutritional supplements, and food products, ensuring consistent amino acid composition across batches is critical for maintaining quality and safety.

 

Analysis Workflow

At MtoZ Biolabs, our Amino Acid Profile Analysis Service is designed with a robust and efficient workflow to deliver precise and reliable results for diverse research needs:

1. Sample Collection and Preparation

We support a wide range of sample types, including tissues, blood, urine, cell culture media, plant extracts, and food products. Samples are meticulously processed to preserve amino acid integrity and remove interfering substances.

 

2. Protein Hydrolysis

Proteins are hydrolyzed through enzymatic or chemical methods to release bound amino acids, ensuring comprehensive analysis of both free and bound amino acid content.

 

3. Separation and Detection

Utilizing advanced liquid chromatography coupled with mass spectrometry (LC-MS), amino acids are accurately separated and detected with unmatched sensitivity and resolution.

 

4. Data Acquisition

High-precision mass spectrometry generates detailed spectra, providing qualitative identification and quantitative measurements of all amino acids in the sample.

 

5. Data Analysis and Reporting

Our expert team delivers customized reports that include amino acid concentrations, detailed profiles, and statistical insights, tailored to your specific research objectives.

 



 

Why Choose MtoZ Biolabs?

By selecting MtoZ Biolabs for your amino acid profile analysis needs, you gain the following advantages:

• High Precision and Sensitivity: Our use of advanced techniques, such as LC-MS and amino acid analyzers, ensures precise and sensitive analysis.
• Customized Services: We provide tailored analysis solutions based on your specific needs, ensuring each analysis is aligned with your research objectives.
• Reliable and Reproducible Data: Our services adhere to strict quality control standards, ensuring consistency and reliability in experimental results.
• Expert Team: Our experienced research team offers professional technical support and consultation to ensure the success of your project.
• One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

 

Applications

Our Amino Acid Profile Analysis Service provide precise measurement of amino acid composition and concentration in various samples, with key applications in the following areas:

• Research Support: Offers critical data for basic research, protein function studies, and structural biology, enhancing the understanding of protein structure and function.
• Drug Development: Assists in optimizing drug candidates, analyzing biological activity, and ensuring efficacy and stability in pharmaceutical R&D.
• Food and Nutrition: Widely applied in food and nutritional analysis to verify ingredient accuracy and support formulation optimization, boosting product quality and market competitiveness.
• Clinical Diagnostics: Detects amino acid abnormalities in body fluids, providing vital insights for disease diagnosis, nutritional assessments, and personalized treatments.

 

Case Study

Case 1: Amino Acid Profile Analysis Aids Sepsis Biomarker Development

Using HPLC-MS/MS, this study analyzed the amino acid distribution in sepsis patients and healthy controls, identifying specific amino acid concentration changes that distinguish patients from healthy individuals. Methodological validation showed the biomarker's high sensitivity and specificity, supporting early sepsis diagnosis and precision treatment. This highlights the value of Amino Acid Profile Analysis Service in biomarker development and precision medicine.

 



Ahn, S. et al. Clin Nutr. 2021.

 

Case 2: Amino Acid Profile Analysis Helps Optimize Plant Protein

In this study, the INFOGEST in vitro digestion method and MALDI-TOF MS were used to examine how the absence of antinutritional factors in pea seeds affects protein digestibility and amino acid bioavailability. Results indicated that triple mutants significantly improved bioavailability and digestibility while maintaining protein concentration and yield. This demonstrates the significant role of Amino Acid Profile Analysis Service in protein functional analysis and plant protein optimization, providing robust data for functional food development and crop enhancement.

 



Olías, R. et al. Food Res. Int. 2023.

 

What Could be Included in the Report?

1. Comprehensive Experimental Details

2. Materials, Instruments, and Methods

3. Total Ion Chromatogram & Quality Control Assessment

4. Data Analysis, Preprocessing, and Estimation

5. Bioinformatics Analysis

6. Raw Data Files

 

Our Amino Acid Profile Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.