α-Muricholic Acid Analysis Service

    α-Muricholic acid (α-MCA) is a bile acid predominantly found in rodents, such as mice and rats, produced during the synthesis of primary bile acids in the liver. α-MCA is known for its unique chemical structure and biological functions, significantly impacting cholesterol metabolism, gut microbiota composition, and liver health. It plays a crucial role in maintaining liver function and regulating bile acid pathways. Research indicates that α-MCA may have biological effects in regulating bile acid metabolism, reducing inflammation, and protecting the liver. Therefore, accurate analysis of α-MCA levels and metabolic changes is essential for understanding its role in both health and disease.

     

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    Figure 1. Molecular Structure of α-Muricholic Acid

     

    MtoZ Biolabs offers α-Muricholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in α-MCA detection.

     

    Analysis Workflow

     

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    Service Advantages

    1. High Sensitivity and Precision

    HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of α-MCA.

     

    2. Rapid and Efficient

    Optimized sample preparation and fast analysis ensure quick and efficient processing.

     

    3. Wide Applicability

    Suitable for various biological samples, including blood, urine, feces, and tissues.

     

    4. Accurate and Reliable Data

    Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

     

    Sample Submission Requirements

    Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

     

    Applications

    • Investigate α-MCA's role in bile acid pathways and explore its biological functions in health and disease.
    • Assess α-MCA's metabolic changes in liver diseases and explore its potential protective role.
    • Study the effects of new drugs on α-MCA metabolism, aiding drug development and efficacy validation.
    • Explore interactions between α-MCA and gut microbiota, investigating its role in gut health regulation.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on α-Muricholic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    Our α-Muricholic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.

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