α-KIV Analysis Service

    α-KIV (α-Ketoisovaleric acid) is a keto acid compound with the chemical structure C₅H₈O₃, consisting of a keto group and an isovaleric acid group. It is primarily produced through the metabolism of the branched-chain amino acid valine, resulting from the deamination of valine, and is widely present in plants and organisms. α-KIV plays an important role in energy metabolism, amino acid metabolism, and the regulation of cell growth. Its metabolites, including isovaleric acid, are crucial for cellular energy production and metabolic regulation. Analyzing the content of α-KIV and its metabolites in plant and biological samples helps to study the biological functions of branched-chain amino acid metabolism, especially in plant growth regulation, metabolic disease research, and bioenergetics. This is significant for understanding plant growth and development mechanisms, improving crop production, and managing human health.

     

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    Figure 1. The Structure of α-KIV

     

    MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, provides advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs utilizes advanced LC-MS-based metabolomics analysis tools to provide comprehensive α-KIV analysis service. We guarantee the precision in the quantification of α-KIV and its metabolites, along with thorough and accurate identification of metabolites. If you have any interest in our α-KIV analysis service, please do not hesitate to contact us. We are fully committed to delivering high-quality analytical services and technical support.

     

    Analysis Workflow

     

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    Service Advantages

    1. Advance Analysis Platform: MtoZ Biolabs established an advanced α-KIV analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

     

    2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

     

    3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all α-KIV analysis data, delivering clients a detailed and comprehensive data report.

     

    4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.

     

    Applications

    • Discovering new disease biomarkers  
    • Enhancing disease diagnosis  
    • Speeding up the discovery of innovative therapeutics  
    • Uncovering new insights into disease mechanisms

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. A minimum of 3 samples with the same condition should be selected for each type of sample.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Sample Preservation

    Samples should be stored at -80°C to ensure stability.

     

    Note: Please provide detailed information on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on α-KIV

    4. Raw Data

    5. Custom Analysis Report

     

    Our α-KIV analysis service is designed to speed up your research and product development by providing precise and reliable results.

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