Active Exosome Isolation Service
- Animal Tissues: Tumor and normal tissues, brain tissue, liver tissue, lung tissue, kidney tissue, adipose tissue, muscle tissue, bone tissue, connective tissue, etc.
- Plant Tissues: Seeds, fruits, flowers, leaves, roots, and stems.
- Blood, urine, cerebrospinal fluid, saliva, tears, breast milk, amniotic, synovial fluids, semen, sweat, etc.
- Animal Cell: Stem cell, cancer cell, T cell, macrophages, dendritic cell, mesenchymal stem cell, neurons, etc.
- Plant Cell: Vegetables, fruits, flowers, etc.
- Microbial Cell: Bacterial, fungal, yeast, algal, etc.
- Basic Biological Research: Investigating exosome biogenesis, composition, and intercellular communication.
- Drug Delivery System Research: Developing exosome-based carriers for targeted drug delivery and controlled release.
- Disease Diagnosis and Therapy: Exploring exosomes as biomarkers for disease detection and therapeutic applications.
- Agricultural and Environmental Science: Studying plant and microbial exosomes for crop improvement and environmental monitoring.
- Food Science: Utilizing exosomes in functional foods, dietary supplements, and bioactive ingredient delivery.
- Cosmetic Innovation: Integrating exosomes into skincare and beauty formulations for enhanced efficacy.
Exosomes are small extracellular vesicles secreted by various cell types, including tumor cells, immune cells, and stem cells. They are encapsulated in a lipid bilayer and carry a wide range of bioactive molecules, such as proteins, lipids, RNA, and DNA, making them pivotal in cellular communication. These vesicles play a significant role in regulating key biological processes, including immune modulation, antigen presentation, cell signaling, and disease progression. However, conventional exosome isolation methods often compromise their structural integrity and biological activity, limiting their effectiveness in downstream applications. MtoZ Biolabs offers an Active Exosome Isolation Service that isolates exosomes while preserving both their morphology and bioactivity.
Exosomes are found in various biological fluids such as blood, urine, saliva, and cerebrospinal fluid, making them a convenient source for non-invasive biomarkers and therapeutic targets. Their ability to carry molecular cargo across biological barriers makes them ideal candidates for targeted drug delivery systems and therapeutic interventions. For example, exosomes derived from immune cells can be harnessed to modulate immune responses, while those from cancer cells may be analyzed to uncover biomarkers or therapeutic targets specific to tumor types.
Figure 1. The Multiple Functions of Exosomes
Service at MtoZ Biolabs
MtoZ Biolabs uses advanced techniques such as differential ultracentrifugation (dUC), ultrafiltration (UF), immunoaffinity (IA), size exclusion chromatography (SEC), and Microfluidics (MF) technology to capture exosomes that exhibit active functions, ensuring they are biologically relevant and suitable for specific downstream applications. With our Active Exosome Isolation Service, MtoZ Biolabs provides a high-purity, functionally intact exosome preparation. Additionally, we offer comprehensive service, including exosome characterization and functional assays, ensuring that the exosomes meet your specific research or therapeutic needs. Whether for biomarker discovery, drug delivery applications, or disease mechanism research, our services ensure you receive reliable and biologically active exosomes, advancing your scientific goals.
Figure 2. Conventional and Novel Methods of Exosome Isolation
Active Exosome Isolation Services from Various Sources
1. Tissues
2. Body Fluids
3. Cell Culture Supernatants
Why Choose MtoZ Biolabs?
✅Preservation of Exosome Integrity: Our methods minimize vesicle disruption, maintaining natural morphology and bioactivity.
✅Optimized Isolation Strategies: We employ SEC, ultrafiltration, and affinity-based purification to selectively capture functionally relevant exosomes.
✅High Purity and Activity: Ensuring minimal contamination and maximum biological function for downstream applications.
✅Tailored Solutions: Customizable active exosome isolation protocols to meet specific research and therapeutic needs.
Applications
Our Active Exosome Isolation Service is applicable in various sectors including but not limited to:
FAQ
Q: How do you ensure high-quality exosome isolation with optimal purity and yield?
We ensure high-quality exosome isolation with optimal purity and yield by employing advanced separation technologies, including ultracentrifugation, size-exclusion chromatography (SEC), and immunoaffinity capture. Our optimized protocols minimize contaminants such as protein aggregates and cellular debris while preserving exosome integrity and biological activity.
MtoZ Biolabs' Active Exosome Isolation Service not only improves the efficiency of exosome isolation but also ensures that the bioactivity of the exosomes is maintained, which is crucial for accurate results in therapeutic and diagnostic applications. Contact us to explore tailored solutions for your research!
How to order?
