9S,11R-dihydroxy-15-oxo-13E-prostaenoic Acid Analysis Service
- Comprehensive profiling and quantification of 9S,11R-Dihydroxy-15-oxo-13E-prostaenoic acid in various samples.
- Revealing the role of 9S,11R-Dihydroxy-15-oxo-13E-prostaenoic acid in biological systems.
- Expediting your research in related disease mechanism and drug discovery.
- Drug Discovery and Development: Evaluate the efficacy and side effects of drugs.
- Disease Research: Understand the role of 9S,11R-Dihydroxy-15-oxo-13E-prostaenoic acid in disease progress.
- Food Science: Investigate the impact of diet on 9S,11R-Dihydroxy-15-oxo-13E-prostaenoic acid level.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
9S,11R-Dihydroxy-15-oxo-13E-prostaenoic acid, also known as 15-keto Prostaglandin F1α (15-keto PGF1α), is the initial metabolite of Prostaglandin F1α (PGF1α) formed via the enzymatic action of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy PGDH). The oxidation of PGF1α to 15-keto PGF1α represents a key step in the deactivation of prostaglandin signaling, particularly related to smooth muscle contraction, vasodilation, and inflammatory regulation. This oxidation at the C-15 position significantly reduces the receptor binding affinity and biological activity of PGF1α in mammals. However, in fish, these compounds act as post-ovulatory pheromones and have been found to be even more biologically active than their parent prostaglandins, highlighting their significance in reproductive signaling and behavior.
The study of 15-keto PGF1α is important for understanding prostaglandin metabolism, receptor interactions, and the broader implications of prostanoid signaling across different species. Its involvement in reproductive physiology in fish, as well as its regulatory role in inflammation and smooth muscle contraction in mammals, underscores the compound's biological versatility. Moreover, as a metabolite of prostaglandins, its measurement is crucial in both clinical research and pharmacological studies aimed at modulating prostaglandin activity for therapeutic purposes.
Figure 1. The Structure of 9S,11R-dihydroxy-15-oxo-13E-prostaenoic Acid
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption.
At MtoZ Biolabs, we offer highly sensitive and reliable 9S,11R-Dihydroxy-15-oxo-13E-prostaenoic acid analysis service using advanced LC-MS/MS system. We can assist you in:
Analysis Workflow
Service Advantages
1. Advance Analysis Platform
MtoZ Biolabs established an advanced 9S,11R-dihydroxy-15-oxo-13E-prostaenoic acid analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality
Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all 9S,11R-dihydroxy-15-oxo-13E-prostaenoic acid analysis service data providing clients with a comprehensive data report.
4. Fast Turnaround
The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Our 9S,11R-Dihydroxy-15-oxo-13E-prostaenoic acid analysis service can facilitate your research in various fields, including but not limited to:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is advised that more than 3 biological replicates should be prepared.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 9S,11R-dihydroxy-15-oxo-13E-prostaenoic Acid
4. Raw Data
5. Custom Analysis Report
For more details about our 9S,11R-Dihydroxy-15-oxo-13E-prostaenoic acid analysis service, please don't hesitate to contact us at MtoZ Biolabs.
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