9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic Acid Analysis Service

9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid, commonly referred to as a key derivative of thromboxane biosynthesis, is a potent bioactive lipid involved in the regulation of vascular homeostasis, platelet aggregation, and inflammatory responses. Structurally, it features hydroxyl groups at the 9α, 11, and 15S positions and a conjugated diene system, which imparts significant bioactivity within thromboxane-mediated pathways. It plays a crucial role in modulating vascular tone and platelet function, making it a focus of research in cardiovascular diseases, including thrombosis, atherosclerosis, and hypertension. It is a direct metabolite of thromboxane A2, a well-known eicosanoid that promotes platelet aggregation and vasoconstriction. Given the delicate balance required for proper vascular function, dysregulation of thromboxane metabolism has been linked to a variety of pathological conditions, from heart attacks to strokes.

 

Accurate profiling of 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid levels can offer insights into disease mechanisms and the effectiveness of anti-thrombotic treatments. Studies in pharmacology and clinical research often focus on this molecule to develop new strategies for mitigating the risks of excessive platelet aggregation and related vascular complications.

 



 

Figure 1. The Structure of 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic Acid

 

At MtoZ Biolabs, we offer comprehensive 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid analysis service using advanced mass spectrometry techniques. Our service can help you:

• Identify and quantify 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid in your samples.
• Understand the metabolic pathway of the substance.
• Evaluate the effect of drug intervention on its metabolism.

 

Analysis Workflow

 



 

Service Advantages

• Expertise: Our team consists of highly trained and experienced scientists who are experts in mass spectrometry and metabolomics.
• Advanced Techniques: We use state-of-the-art mass spectrometry techniques, providing high accuracy and sensitivity.
• Customized Service: We offer personalized service to meet your specific research needs.
• Confidentiality: We guarantee the confidentiality and integrity of your data.

 

Applications

Our service can be applied in different fields, including:

• Biomarker discovery
• Drug development and pharmacokinetics studies
• Pathological research
• Nutritional studies

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

 

Note: Please provide details on sample collection and handling.

 

Deliverables

1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic Acid

4. Raw Data

5. Custom Analysis Report

 

Contact us today to learn more about how our 9α,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid analysis service can support your research.