9-oxo-15S-hydroxy-5Z,10Z,13E-prostatrienoic Acid Analysis Service
- Biomarker identification in disease research
- Investigation of metabolism pathways
- Drug response prediction
- Basic biological research
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
9-oxo-15S-hydroxy-5Z,10Z,13E-prostatrienoic acid, also known as Prostaglandin A2 (PGA2), is a biologically active lipid derived from membrane phospholipids, specifically from the dehydration of Prostaglandin E2 (PGE2). Prostaglandins, including PGA2, are composed of C20 unsaturated fatty acids with a cyclopentane ring, and they play critical roles in regulating a wide range of physiological and pathological processes, including inflammation, immune responses, and cell signaling.
PGA2 has been extensively studied for its antitumor properties. It induces the expression of γ-glutamylcysteine synthetase and promotes apoptosis in cells. Additionally, PGA2 inhibits the growth of Friend erythroleukemia cells, stimulating their differentiation, causing cell cycle arrest in the G1 phase. Importantly, PGA2 has also been shown to inhibit viral replication at non-toxic doses, demonstrating its potential as an antiviral agent. Recent studies indicate that PGA2 can activate the intrinsic apoptosis pathway by directly stimulating mitochondrial outer membrane permeabilization, leading to cytochrome C release.
Figure 1. The Structure of 9-oxo-15S-hydroxy-5Z,10Z,13E-prostatrienoic Acid
The wide-ranging effects of PGA2, from its antitumor and antiviral activities to its role in apoptosis, make it a key target for research. Understanding its biological functions and mechanisms is crucial for developing therapeutic strategies in cancer treatment, viral infections, and immune regulation.
To support advanced research in this field, MtoZ Biolabs offers a specialized 9-oxo-15S-hydroxy-5Z,10Z,13E-prostatrienoic Acid (Prostaglandin A2) Analysis Service. MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Using cutting-edge mass spectrometry, our service provides accurate and reliable quantification of PGA2, ensuring high-quality data for researchers studying its role in cancer biology, immune regulation, and apoptosis.
Analysis Workflow
Service Advantages
1. Advance Analysis Platform
MtoZ Biolabs established an advanced 9-oxo-15S-hydroxy-5Z,10Z,13E-prostatrienoic acid analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality
Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all 9-oxo-15S-hydroxy-5Z,10Z,13E-prostatrienoic acid analysis service data providing clients with a comprehensive data report.
4. Fast Turnaround
The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is advised to prepare more than 3 biological replicates.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 9-oxo-15S-hydroxy-5Z,10Z,13E-prostatrienoic Acid
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to providing high-quality 9-oxo-15S-hydroxy-5Z,10Z,13E-prostatrienoic Acid Analysis Service to aid your research. Contact us today to learn more about our services.
How to order?
