8-iso 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic Acid Analysis Service
- Detection and quantification of 8-iso-PGF2α in various samples
- Comprehensive interpretation of the metabolic data
- Detailed report with bioinformatics analysis
- Clinical diagnostics
- Biomarker discovery
- Pharmaceutical research
- Disease progression studies
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
8-iso 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, commonly known as 8-iso-Prostaglandin F2α (8-iso-PGF2α), is a biologically active isoprostane, which originates from the non-enzymatic peroxidation of arachidonic acid. Unlike traditional prostaglandins, isoprostanes such as 8-iso-PGF2α are formed by free radical-catalyzed reactions that proceed through bicyclic endoperoxide intermediates. These intermediates are reduced to generate ring isoprostanes, which are initially esterified in phospholipids and later released into circulation, likely via the action of phospholipases. This non-enzymatic pathway is significant both from a biochemical and biological standpoint, offering insights into oxidative stress mechanisms and lipid peroxidation. Additionally, 8-iso-PGF2α has been recognized as a potent renal vasoconstrictor and plays a pivotal role in vascular homeostasis.
Due to its potent biological activities and association with oxidative stress, the precise measurement of 8-iso-PGF2α is crucial in understanding its role in disease progression, vascular dysfunction, and inflammation. Research into its activity can help uncover new therapeutic strategies for treating oxidative stress-related conditions.
Figure 1. The Structure of 8-iso 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic Acid
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption.
At MtoZ Biolabs, we provide comprehensive 8-iso-PGF2α analysis services using advanced LC-MS/MS systems.
Analysis Workflow
Service Advantages
1. Advance Analysis Platform
MtoZ Biolabs established an advanced 8-iso 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality
Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all 8-iso 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid analysis service data providing clients with a comprehensive data report.
4. Fast Turnaround
The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Our service is suitable for:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 8-iso 9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic Acid
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to providing high-quality, reliable and efficient analytical services to meet your research needs.
How to order?
