6-hydroxy Melatonin Analysis Service

    6-hydroxy melatonin, with the chemical formula C13H16N2O3, has a structure similar to melatonin, differing only by the introduction of a hydroxyl (-OH) group at the 6th carbon position. While the primary functions of 6-hydroxy melatonin are not yet fully elucidated, research suggests that it may be involved in antioxidant and anti-inflammatory responses. Melatonin itself has strong antioxidant properties, and 6-hydroxy melatonin, with the additional hydroxyl group, may enhance these properties. It can scavenge free radicals in the body, reducing oxidative stress and cellular damage.

     

    The levels of 6-hydroxy melatonin in biological samples can serve as an indicator of melatonin metabolism, helping researchers understand an individual's melatonin metabolic capacity as well as related physiological or pathological states. For example, levels of 6-hydroxy melatonin may change in conditions such as sleep disorders, liver dysfunction, or under the influence of certain medications. Therefore, measuring 6-hydroxy melatonin has potential applications in clinical and research contexts. MtoZ Biolabs employs an advanced liquid chromatography-mass spectrometry (LC-MS) platform and a skilled metabolomics team to perform in-depth 6-hydroxy melatonin analysis service. We assure high sensitivity and precision in the analysis.

     

    1828263663543898112-TheStructureof6-hydroxyMelatonin.png

    Figure 1. The Structure of 6-Hydroxy Melatonin

     

    Analysis Workflow

    Our 6-Hydroxy Melatonin Analysis Service is based on liquid chromatography-mass spectrometry (LC-MS), which separates and identifies the metabolites based on their mass-to-charge ratio.

     

    1828263888027242496-Workflowof6-hydroxyMelatoninAnalysisService.PNG

     

    Service Advantages

    • Highly sensitive and accurate
    • Rapid turnaround time
    • Comprehensive data analysis
    • Highly skilled and knowledgeable team

     

    Applications

    • Qualitative and quantitative analysis of 6-hydroxy melatonin
    • Study of melatonin metabolism and circadian rhythms
    • Development of therapeutics and nutritional supplements

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues and other biological samples. More than 3 samples of the same condition are required.

     

    2. Sample Volume

    At least 200 μL of liquid sample; At least 200 mg of solid tissues.

     

    3. Sample Preservation

    Store at -80°C to maintain stability.

     

    Note: Provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on 6-Hydroxy Melatonin

    4. Raw Data

    5. Custom Analysis Report

     

    Our 6-Hydroxy Melatonin Analysis Service aims to provide consistent and reliable results, facilitating your research and product development efforts.

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