5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic Acid Analysis Service
- Provide precise quantification of 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid using the state-of-the-art LC-MS/MS platform.
- Perform comprehensive metabolic profiling that can reveal significant changes in metabolism.
- Identify potential biomarkers associated with pathological conditions.
- Disease Diagnosis
- Drug Efficacy Studies
- Metabolic Pathway Studies
- Biomarker Discovery
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid, also known as Leukotriene D4 (LTD4), is a biologically significant eicosanoid derived from arachidonic acid, playing an essential role in inflammation and immune response regulation. This molecule is part of the cysteinyl-leukotriene (CysLTs) family, which is known for its involvement in allergic reactions and inflammatory processes. Structurally, 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid features a hydroxyl group at the 5S position and a cysteinylglycinyl moiety attached to the 6R position, making it a unique bioactive lipid involved in cellular signaling.
This metabolite is generated through the lipoxygenase pathway, where arachidonic acid undergoes enzymatic modifications to form various cysteinyl-leukotrienes. These compounds are critical mediators of inflammatory responses, particularly in conditions like asthma, allergic rhinitis, and cardiovascular diseases. As a key participant in the leukotriene pathway, 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid interacts with CysLT receptors, influencing bronchoconstriction, vascular permeability, and immune cell recruitment to sites of inflammation. The accurate measurement of this compound is crucial for understanding its role in inflammation and for exploring its potential as a biomarker in allergic and cardiovascular conditions. Additionally, quantifying this eicosanoid aids in the development of therapeutic strategies targeting cysteinyl-leukotriene pathways.
Figure 1. The Structure of 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic Acid
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, providing advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs offers a specialized 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic Acid Analysis Service. Our team of experts can help you:
Analysis Workflow
Service Advantages
1. Advance Analysis Platform
MtoZ Biolabs established an advanced 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality
Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid analysis service data providing clients with a comprehensive data report.
4. Fast Turnaround
The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11Z,14Z-eicosatetraenoic Acid
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is committed to accelerating your research with our comprehensive metabolomics services. Trust us to deliver accurate, reliable, and timely results for your analysis needs.
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