5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic Acid Analysis Service
- Accurate quantification of 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic acid in various biological samples.
- In-depth metabolic pathway analysis.
- Profiling and identification of associated lipid metabolites.
- Advanced LC-MS/MS systems for high sensitivity and accuracy.
- A team of experts with deep knowledge in metabolomics and lipidomics.
- Comprehensive service from sample preparation to data analysis.
- Rapid turnaround time and competitive pricing.
- Biomarker discovery for diseases.
- Drug metabolism studies.
- Mechanistic studies of disease progression.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic acid is a bioactive lipid mediator derived from arachidonic acid, playing a crucial role in inflammatory signaling and immune responses. This metabolite is produced via the enzymatic conversion of arachidonic acid through the action of lipoxygenases and glutathione-dependent enzymes. Structurally, it features a hydroxyl group at the 5S position and a cysteinyl group at the 6R position, along with a conjugated tetraene system. These structural features allow it to participate in various biochemical pathways, particularly those involved in immune modulation and inflammation. This molecule belongs to the cysteinyl-leukotrienes (CysLTs) family, known for their roles in mediating inflammatory responses, especially in allergic reactions, asthma, and other respiratory diseases. CysLTs, including 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic acid, act by binding to CysLT receptors, promoting bronchoconstriction, increased vascular permeability, and recruitment of immune cells to sites of inflammation.
Understanding and quantifying this molecule is essential in the study of inflammatory diseases, particularly those involving respiratory and cardiovascular systems. The accurate detection of 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic acid levels in biological samples provides valuable insight into the pathophysiology of inflammatory disorders and aids in the development of targeted anti-inflammatory therapies.
Figure 1. The Structure of 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic Acid
At MtoZ Biolabs, we provide a comprehensive analysis service for 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic acid, offering:
Analysis Workflow
Service Advantages
At MtoZ Biolabs, we have:
Applications
Our 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic acid analysis service is applicable in:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic Acid
4. Raw Data
5. Custom Analysis Report
Contact us now to know more about our 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11E,14Z-eicosatetraenoic Acid Analysis Service and how we can assist with your research.
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