5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic Acid Analysis Service

    5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid is a metabolite of arachidonic acid. It is formed by the action of 5-lipoxygenase on arachidonic acid, and further metabolized by human neutrophils to form leukotriene B4, a potent chemotactic agent and promoter of leukotriene production. The structural characteristics of 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid consist of four double bonds and three hydroxyl groups, adding to its biological activity. 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid is involved in various biological processes, such as inflammation, cell proliferation, vascular tone, and chemotaxis. The dysregulation of its metabolism has been associated with various pathological conditions, including cardiovascular diseases, cancers, and inflammatory disorders. Therefore, understanding the dynamics and regulation of 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid can provide critical insights into these diseases and potential therapeutic strategies.

     

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    Figure 1. The Structure of 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic Acid

     

    MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, providing advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption.

     

    At MtoZ Biolabs, we offer advanced 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic Acid Analysis Service. Our service offerings include:

    • Identifying and quantifying 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid in various biological samples using our state-of-the-art mass spectrometry platforms.
    • Investigating the metabolic pathways and regulatory mechanisms of 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid.
    • Discovering potential biomarkers related to the dysregulation of 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid metabolism.

     

    Analysis Workflow

     

    1843831564858413056-Workflowfor5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoicAcidAnalysisService.png

     

    Service Advantages

    • State-of-the-art LC-MS platforms
    • Professional team with expertise in lipidomics
    • Comprehensive data analysis
    • Strict quality assurance and quality control
    • Customizable to your specific requirements

     

    Applications

    • Biomarker Discovery
    • Drug Development
    • Dietary and Nutritional Studies

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Storage and Shipping

    Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

     

    Note: Please provide details on sample collection and handling.

     

    Deliverables

    1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    Contact us today to discuss your project and how MtoZ Biolabs can help you with your 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid analysis needs.

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