5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic Acid Analysis Service

    5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid is a bioactive lipid derived from arachidonic acid and is known for its role in modulating inflammation and immune responses. As a metabolite in the lipoxygenase pathway, this compound is produced through enzymatic reactions involving 5-lipoxygenase (5-LOX) and 12-lipoxygenase (12-LOX). Structurally, it contains hydroxyl groups at the 5S, 12R, and 20 positions, along with a conjugated tetraene system, which enables it to participate in the regulation of complex biochemical processes in the body. This eicosanoid plays an important role in various physiological and pathological processes, particularly in inflammatory diseases. It functions by interacting with cell surface receptors to regulate leukocyte trafficking, cytokine production, and other key aspects of immune response.

     

    1843887711183294464-TheStructureof5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoicAcid.png

     

    Figure 1. The Structure of 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic Acid

     

    MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, providing advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption.

     

    At MtoZ Biolabs, we offer comprehensive 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid analysis service. By deploying advanced mass spectrometry techniques and our expertise in metabolomics, we can help you:

    • Determine the concentration of 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid in different samples.
    • Understand the metabolic pathways and biological functions of this metabolite.
    • Identify potential targets for disease intervention.

     

    Analysis Workflow

     

    1843884400120025088-Workflowfor5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoicAcidAnalysisService.png

     

    Service Advantages

    • State-of-the-art facilities and experienced scientists.
    • Comprehensive service from sample preparation to data interpretation.
    • Accurate and reliable results with short turnaround time.

     

    Applications

    • Research on inflammation and related diseases.
    • Drug development targeting arachidonic acid metabolism.

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Storage and Shipping

    Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

     

    Note: Please provide details on sample collection and handling.

     

    Deliverables

    1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    With our expertise and commitment to excellence, MtoZ Biolabs is your ideal partner in exploring the fascinating world of metabolomics. We look forward to supporting your research on 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid.

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