5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic Acid Analysis Service
- Targeted metabolomics approach for the absolute quantification of RvE1.
- High sensitivity and accuracy.
- Comprehensive report with results interpretation.
- High accuracy and reproducibility.
- Experienced team of scientists with expertise in metabolomics.
- High-throughput platform to handle large sample sets with quick turnaround times.
- Competitive pricing for cost-effective analysis service.
- Inflammation Research.
- Immunology.
- Neuroscience.
- Drug Discovery.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid, commonly referred to as resolvin E1 (RvE1), is a specialized pro-resolving lipid mediator derived from eicosapentaenoic acid (EPA). RvE1 plays a crucial role in actively resolving inflammation, promoting the clearance of inflammation-induced cellular debris, and restoring tissue homeostasis. It is characterized by three hydroxyl groups at positions 5, 12, and 18, along with several conjugated double bonds, which contribute to its potent biological functions. Research on RvE1 has demonstrated its importance in regulating immune responses and mitigating excessive inflammation. Unlike classic pro-inflammatory mediators, resolvins like RvE1 help resolve inflammation without suppressing the immune system, making them ideal candidates for therapeutic interventions in chronic inflammatory diseases. Studies have shown that RvE1 is involved in reducing neutrophil infiltration, stimulating macrophage-mediated clearance of apoptotic cells, and limiting further tissue damage. Its involvement in diseases such as cardiovascular conditions, periodontal disease, and neuroinflammation has made it a key target for research.
The study of RvE1 is of immense scientific and therapeutic interest as it provides insights into the pathogenesis of chronic inflammatory and neurological diseases. The precise quantification of RvE1 enables researchers to understand its role in disease pathology and facilitates the development of therapeutic strategies targeting the resolution phase of inflammation.
Figure 1. The Structure of 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic Acid
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, providing advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption.
MtoZ Biolabs offers a comprehensive 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic Acid Analysis Service. We utilize cutting-edge LC-MS/MS technologies for the quantitative analysis of RvE1. Our services include:
Analysis Workflow
Service Advantages
Applications
Our service is applicable to various research areas, including but not limited to:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic Acid
4. Raw Data
5. Custom Analysis Report
Our dedicated team of experts is committed to providing you with the most accurate and comprehensive 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic Acid Analysis Service. Let MtoZ Biolabs be your trusted partner in your research journey.
How to order?
