5α-Cholanic Acid-3α-Ol Analysis Service

5α-Cholanic acid-3α-ol (alloLCA) is a significant intermediate metabolite in bile acid metabolism, recognized for its unique biological activity. alloLCA is formed through enzyme-catalyzed reactions within the bile acid metabolism pathway and is widely distributed in the liver, bile, and intestines. Research indicates that alloLCA plays a crucial role in bile acid metabolism, cholesterol regulation, and maintaining liver function. Abnormal levels of alloLCA are closely associated with various metabolic and liver diseases, making precise analysis of this compound essential for understanding its roles in both physiological and pathological conditions.

 



Figure 1. Molecular Structure of 5α-Cholanic Acid-3α-Ol

 

MtoZ Biolabs offers 5α-Cholanic Acid-3α-Ol Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in alloLCA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity and Precision

HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of alloLCA.

 

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

 

3. Wide Applicability

Suitable for various biological samples, including blood, urine, feces, and tissues.

 

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

 

Sample Submission Requirements

Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 5α-Cholanic Acid-3α-Ol

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into alloLCA's extensive physiological roles through top-tier analytical techniques and expert services.