5-methyl-2'-deoxycytidine Analysis Service

    5-methyl-2'-deoxycytidine (5mdC) is a naturally occurring nucleoside present in mammalian DNA. It is a product of DNA methylation, which is a biochemical process crucial for normal development in higher organisms. 5mdC is typically formed by adding a methyl group to the carbon 5 position of the cytosine ring via the DNA methylation pathway. The methylation of cytosine residues in DNA is an important epigenetic modification associated with gene expression, X-chromosome inactivation, genomic imprinting, and genome stability. Alterations in DNA methylation patterns can lead to various human diseases, including cancer.

     

    5mdC plays a central role in transgenerational epigenetic inheritance, genomic stability, and gene expression. It is also a key biomarker for cancer diagnosis and prognosis. Thus, the analysis of 5mdC is essential for understanding the molecular mechanisms that regulate cellular processes and disease development.

     

    1836608427884400640-TheStructureof5-methyl-2'-deoxycytidine.png

     

    Figure 1. The Structure of 5-methyl-2'-deoxycytidine

     

    At MtoZ Biolabs, we offer an advanced 5-methyl-2'-deoxycytidine analysis service using Ultra Performance Liquid Chromatography and Tandem mass spectrometry (UPLC-MS/MS), providing accurate quantification of 5mdC in various sample types. Our specialized team of scientists offer comprehensive analyses, from sample preparation to data interpretation, enabling you to focus on your research.

     

    Analysis Workflow

     

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    Service Advantages

    • Highly Efficient Sample Recovery and Processing
    • Accurate and Reliable Detection and Quantification
    • Capability to Handle Various Sample Types
    • Customized Data Analysis Services
    • Rapid Service Response and Cost-Effectiveness

     

    Applications

    Our 5mdC analysis service can be applied in various research fields, including but not limited to:

    • Epigenetic studies
    • Cancer research
    • Biomarker discovery
    • Therapeutic development

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Storage and Shipping

    Samples should be stored at -80℃ and shipped with dry ice.

     

    Note: Please provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on 5-methyl-2'-deoxycytidine

    4. Raw Data

    5. Custom Analysis Report

     

    With MtoZ Biolabs, you can be assured of receiving the most precise and reliable 5-methyl-2'-deoxycytidine analysis service. Let us help you accelerate your research with our dedicated service and exceptional expertise.

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