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    5-methoxyuridine Analysis Service

      5-methoxyuridine is a modified nucleoside where a methoxy group (-OCH₃) is attached to the 5th carbon of the uridine base. This modification, though less common than other uridine derivatives, has been observed in certain RNA molecules, particularly in transfer RNA (tRNA), where it plays a role in stabilizing RNA structure and facilitating accurate protein translation. By contributing to the wobble position in tRNA, 5-methoxyuridine helps ensure proper codon-anticodon interactions during the decoding process, thus supporting the fidelity of protein synthesis.

       

      In addition to its role in tRNA, 5-methoxyuridine has attracted interest in biochemical research due to its potential involvement in regulating RNA function and cellular responses. Modifications like 5-methoxyuridine can impact RNA stability, folding, and interactions with other biomolecules, making them important in various cellular processes. Research has suggested that such modifications may also be linked to stress responses, development, and adaptation mechanisms, as they provide an additional layer of control over gene expression.

       

      1838402726968020992-TheStructureof5-methoxyuridine.png

       

      Figure 1. The Structure of 5-methoxyuridine

       

      MtoZ Biolabs offers a specialized 5-methoxyuridine Analysis Service using cutting-edge mass spectrometry technology for precise detection and quantification. Our service supports research in RNA modifications, nucleoside metabolism, and therapeutic development, providing high-quality data to advance investigations into the role of modified nucleosides like 5-methoxyuridine in health and disease.

       

      Analysis Workflow

       

      1838400920581951488-Workflowfor5-methoxyuridineAnalysisService.png

       

      Service Advantages

      • Extensive experience in various biological sample preparation techniques
      • Professional standard operating procedure
      • State-of-the-art facilities and equipment for precise analysis
      • Expert team with extensive experience in metabolomics
      • Comprehensive data analysis
      • Excellent customer service and after-service support

       

      Applications

      Our 5-Methoxyuridine Analysis Service can be applied in:

      • Disease Diagnosis: Detecting changes in 5-Methoxyuridine levels can help in diagnosing diseases such as cancer and neurological disorders.
      • Drug Development: Understanding the role of 5-Methoxyuridine in disease pathogenesis can aid in developing new therapeutic strategies.
      • RNA Modification Studies: Analyze 5-Methoxyuridine's role in RNA modification processes.
      • Epigenetic Research: Investigate its influence on gene expression and regulation.

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Storage and Shipping

      Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 5-methoxyuridine

      4. Raw Data

      5. Custom Analysis Report

       

      At MtoZ Biolabs, we strive to provide high-quality, accurate, and reliable 5-Methoxyuridine analysis service. If you have any questions or need assistance, please don't hesitate to contact us.

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