5-iodocytidine Analysis Service

    5-Iodocytidine is a modified nucleoside, featuring an iodine atom at the 5-position of the cytidine base. This modification enhances its utility as a critical tool in the fields of nucleic acid and nucleic acid-protein interaction research. 5-Iodocytidine has been used to elucidate the structures of natural base mispairings to explain their mutagenic properties. 5-iodocytidine exhibits significant antitumor activity and functions as a fluorescent probe for detecting uridine in biological samples. Its similarity to uridine enables cellular uptake and incorporation into RNA, facilitating detection through antibody responses and fluorescence microscopy. Additionally, 5-Iodocytidine may have therapeutic potential for infectious and autoimmune diseases by binding to reactive elements on DNA and activating gene transcription.

     

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    Figure 1. The Structure of 5-iodocytidine

     

    Understanding the diverse roles of 5-iodocytidine is essential for exploring its biological and therapeutic potential. At MtoZ Biolabs, we offer comprehensive 5-Iodocytidine analysis services using advanced mass spectrometry techniques. Our team of experts is highly skilled in the extraction, purification, and quantification of 5-Iodocytidine from a variety of sample types.

     

    Analysis Workflow

     

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    Service Advantages

    • State-of-the-art LC-MS/MS platforms allow us to accurately and reliably quantify 5-Iodocytidine in various types of samples.
    • A team of experts in mass spectrometry and metabolomics provides professional data analysis and interpretation.
    • One-stop service from sample preparation, LC-MS/MS analysis to data analysis, saving your time and efforts.
    • Competitive price with high-quality service.

     

    Applications

    Our 5-Iodocytidine analysis service is applicable to both basic research and pharmaceutical research, including but not limited to:

    • Studying DNA replication and RNA transcription.
    • Investigating the molecular mechanisms of diseases.
    • Developing potential therapeutic agents.

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Storage and Shipping

    Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

     

    Note: Please provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on 5-iodocytidine

    4. Raw Data

    5. Custom Analysis Report

     

    At MtoZ Biolabs, we are committed to providing our customers with high-quality and reliable metabolomics services. Contact us today to learn more about our 5-Iodocytidine analysis service.

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