5-iodocytidine Analysis Service

5-Iodocytidine is a modified nucleoside, featuring an iodine atom at the 5-position of the cytidine base. This modification enhances its utility as a critical tool in the fields of nucleic acid and nucleic acid-protein interaction research. 5-Iodocytidine has been used to elucidate the structures of natural base mispairings to explain their mutagenic properties. 5-iodocytidine exhibits significant antitumor activity and functions as a fluorescent probe for detecting uridine in biological samples. Its similarity to uridine enables cellular uptake and incorporation into RNA, facilitating detection through antibody responses and fluorescence microscopy. Additionally, 5-Iodocytidine may have therapeutic potential for infectious and autoimmune diseases by binding to reactive elements on DNA and activating gene transcription.

Figure 1. The Structure of 5-iodocytidine

Understanding the diverse roles of 5-iodocytidine is essential for exploring its biological and therapeutic potential. At MtoZ Biolabs, we offer comprehensive 5-Iodocytidine analysis services using advanced mass spectrometry techniques. Our team of experts is highly skilled in the extraction, purification, and quantification of 5-Iodocytidine from a variety of sample types.

Analysis Workflow

Service Advantages

• State-of-the-art LC-MS/MS platforms allow us to accurately and reliably quantify 5-Iodocytidine in various types of samples.
• A team of experts in mass spectrometry and metabolomics provides professional data analysis and interpretation.
• One-stop service from sample preparation, LC-MS/MS analysis to data analysis, saving your time and efforts.
• Competitive price with high-quality service.

Applications

Our 5-Iodocytidine analysis service is applicable to both basic research and pharmaceutical research, including but not limited to:

• Studying DNA replication and RNA transcription.
• Investigating the molecular mechanisms of diseases.
• Developing potential therapeutic agents.

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

Note: Please provide details on sample collection and handling.

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 5-iodocytidine

4. Raw Data

5. Custom Analysis Report

At MtoZ Biolabs, we are committed to providing our customers with high-quality and reliable metabolomics services. Contact us today to learn more about our 5-Iodocytidine analysis service.