5-Hydroxytryptamine Analysis Service
- Investigate the role of 5-HT in mood regulation, cognition, and memory, aiding in the study of neurological disorders.
- Monitor the metabolic effects of pharmaceuticals on 5-HT, assessing drug efficacy and side effects.
- Explore vasoconstriction mechanisms, contributing to research on the causes of migraines and related conditions.
- Study the biological roles of 5-HT across various species (including animals, insects, and plants), revealing its function in plant defense mechanisms and animal behavioral diversity
5-Hydroxytryptamine (5-HT), commonly known as serotonin, is a crucial monoamine neurotransmitter extensively distributed in both the central nervous system (CNS) and peripheral tissues. It plays a vital role in regulating an array of physiological functions, including mood, cognition, reward, learning, memory, vomiting, and vasoconstriction. Nearly 90% of 5-HT is synthesized by enterochromaffin cells in the gastrointestinal tract, which are responsible for managing intestinal motility. Additionally, 5-HT is present in Merkel cells of the skin, neuroendocrine cells of the lungs, and taste receptor cells on the tongue. Serotonin is not confined to mammals but is also found in all bilaterians (such as worms and insects), as well as in fungi and plants. Insect venom and plant spines containing serotonin can induce pain, while serotonin produced by pathogenic amoebas may trigger symptoms like diarrhea. Due to its extensive involvement in various biological processes, the quantitative analysis of 5-HT is essential for understanding neurological disorders, gastrointestinal dysfunctions, and for drug development.
Figure 1. Molecular Structure of 5-Hydroxytryptamine
MtoZ Biolabs is dedicated to offering high-quality 5-Hydroxytryptamine Analysis Service. By leveraging advanced mass spectrometry platforms and high-performance liquid chromatography (HPLC-MS), MtoZ Biolabs enables researchers to comprehensively investigate 5-HT fluctuations across different physiological and pathological states, providing robust data support for neuroscience, gastrointestinal research, and drug development.
Analysis Workflow
Service Advantages
Why Choose MtoZ Biolabs?
1. High Sensitivity and Precision: Using HPLC-MS, we accurately quantify even low concentrations of 5-HT in various sample types.
2. Compatibility with Multiple Sample Types: Our technology supports the analysis of biological samples such as blood, urine, cerebrospinal fluid, and intestinal tissues, accommodating diverse research needs.
3. High-Throughput and Rapid Detection: We efficiently process large sample volumes, significantly reducing research timelines.
4. Data Reliability: Rigorous quality control protocols and standardized operational procedures ensure high reproducibility and precision in results.
Sample Submission Requirements
Applications
Deliverables
What Could be Included in the Report?
1. Comprehensive Experimental Details
2. Materials, Instruments, and Methods
3. Total Ion Chromatogram & Quality Control Assessment (project-dependent)
4. Data Analysis, Preprocessing, and Estimation (project-dependent)
5. Bioinformatics Analysis
6. Raw Data Files
Our 5-Hydroxytryptamine Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.
How to order?
