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    5-formyl-2'-O-methylcytidine Analysis Service

      5-formyl-2'-O-methylcytidine (f5Cm) is a modified ribonucleoside. Structurally, f5Cm features a formyl group attached to the 5-position of the cytosine base, along with a 2'-O-methyl group on the ribose sugar. This unique modification is predominantly found in RNA molecules and plays essential roles in regulating RNA stability, translation, and overall cellular function. As a cytidine analog, f5Cm exhibits properties similar to other nucleoside analogs known for their ability to inhibit DNA methyltransferases. These properties suggest that f5Cm may possess potential anti-metabolic and anti-tumor activities, positioning it as a compound of significant interest in cancer research and therapeutic development. The presence of f5Cm in RNA suggests a complex layer of regulation beyond traditional genetic codes, contributing to the dynamic landscape of gene expression.

       

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      Figure 1. The Structure of 5-formyl-2'-O-methylcytidine

       

      MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, providing advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs offers a comprehensive f5Cm analysis service using our advanced LC-MS/MS platform. Our well-experienced scientists can provide accurate quantification and in-depth analysis of f5Cm, assisting you in your biomarker discovery, drug development, and mechanistic studies.

       

      Analysis Workflow

       

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      Service Advantages

      • Highly sensitive and accurate quantification of f5Cm
      • Expert team with extensive experience in metabolomics
      • Comprehensive report with both raw data and in-depth analysis
      • High throughput and fast turnaround time
      • Competitive price

       

      Applications

      Our f5Cm analysis service is widely applied in the fields of biomarker discovery, drug development, and mechanistic studies.

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Storage and Shipping

      Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 5-formyl-2'-O-methylcytidine

      4. Raw Data

      5. Custom Analysis Report

       

      At MtoZ Biolabs, we are committed to providing our clients with the most accurate and comprehensive 5-formyl-2'-O-methylcytidine analysis service. Contact us today to discuss your project needs.

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