4-thiouridine Analysis Service
- Extensive experience in various biological sample preparation techniques
- Professional standard operating procedure
- State-of-the-art facilities and equipment for precise analysis
- Expert team with extensive experience in metabolomics
- Comprehensive data analysis
- Excellent customer service and after-service support
- Investigation of RNA metabolism
- Research on gene regulation
- Studies on cellular stress response
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
4-thiouridine (4sU) is a naturally occurring modified nucleoside. It is present in the tRNA of many species including bacteria, yeast, and mammals. Structurally, 4-thiouridine is an analogue of uridine with a sulfur atom replacing the 4th carbon atom of the uracil ring. 4-thiouridine is involved in various cellular processes, such as the regulation of gene expression, RNA stability, and response to stress conditions. With its ability to absorb ultraviolet light, 4-thiouridine has been used as a photoactivatable crosslinking agent to study RNA-protein interactions. The sulfur atom in 4-thiouridine can catalyze the formation of thiolation, a post-transcriptional modification that modulates tRNA stability and function.
Figure 1. The Structure of 4-thiouridine
At MtoZ Biolabs, we specialize in providing comprehensive 4-thiouridine analysis service. We utilize advanced mass spectrometry technologies coupled with our expertise in metabolomics to deliver accurate and reliable results.
Analysis Workflow
Service Advantages
Applications
Our 4-thiouridine analysis service can support various types of studies, including:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 4-thiouridine
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to providing you with high-quality and reliable 4-thiouridine analysis service. Contact us today to discuss your project needs.
How to order?
