4-Hydroxy-3-methoxymandelic Acid Analysis Service

    4-Hydroxy-3-methoxymandelic acid, also known as vanillylmandelic acid (VMA), is a metabolite of the catecholamines dopamine and epinephrine. It can be derived from the breakdown of catecholamines in the adrenal glands and sympathetic nerves. Structurally, VMA is a member of the class of compounds known as O-methylated hydroxybenzoic acids. These are hydroxybenzoic acids carrying a methoxy group at the benzene ring.

     

    1832990756223700992-TheStructureof4-Hydroxy-3-methoxymandelicAcid.png

     

    Figure 1. The Structure of 4-Hydroxy-3-methoxymandelic Acid

     

    Studying 4-Hydroxy-3-methoxymandelic acid is pivotal for biochemical and physiological research. It serves as an excellent biomarker for diagnosing diseases like neuroblastoma, pheochromocytoma, and paraganglioma. In addition, VMA is a crucial factor in stress response, blood pressure regulation, and neurotransmission.

     

    Our team of experts can help you detect and quantify 4-Hydroxy-3-methoxymandelic acid in various types of samples. We offer a comprehensive 4-Hydroxy-3-methoxymandelic Acid Analysis Service, from sample preparation, metabolite extraction, separation, to detection and quantification.

     

    Analysis Workflow

     

    1832986669415518208-Workflowfor4-Hydroxy-3-methoxymandelicAcidAnalysisService.png

     

    Service Advantages

    • Extensive expertise in handling various biological samples and extracting metabolites.
    • State-of-the-art mass spectrometry platforms: LC-MS, GC-MS, MRM method.
    • Strict quality control to ensure reliable results.
    • Comprehensive statistical and bioinformatics analysis.
    • Personalized service to meet various research needs.

     

    Applications

    • Disease Diagnosis
    • Drug Metabolism Study
    • Nutritional Research
    • Biomarker Discovery

     

    Sample Submission Requirements

     

    1832989421285789696-SampleSubmissionRequirementsof4-Hydroxy-3-methoxymandelicAcidAnalysisService.png

     

    • Samples should be stored at -80℃ and shipped with dry ice.
    • We recommend providing at least 3 samples of similar conditions for each type of sample.
    • Please provide details on sample collection and handling.
    • Other sample types, please contact us for more details.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on 4-Hydroxy-3-methoxymandelic Acid 

    4. Raw Data

    5. Custom Analysis Report

     

    We are dedicated to providing the best service to our clients, and we look forward to working with you on your 4-Hydroxy-3-methoxymandelic Acid Analysis project.

Submit Inquiry
Name *
Email Address *
Phone Number
Inquiry Project
Project Description *

 

How to order?


/assets/images/icon/icon-message.png

Submit Inquiry

/assets/images/icon/icon-return.png