3-Phosphoglyceric Acid Analysis Service
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
3-Phosphoglyceric acid (3-PGA) is an important organic acid molecule classified as a phosphorylated hydroxy acid. Its chemical formula is C₇H₇O₇P, and its molecular weight is 186.06 g/mol. 3-PGA is a key intermediate in the glycolysis pathway and the Calvin cycle. The analysis of 3-PGA is significant for studying cellular metabolism, energy transformation, and carbon fixation processes, and it has broad applications in medical and biological research. Since 3-PGA is a critical intermediate in glycolysis and gluconeogenesis, its metabolic abnormalities may be associated with various metabolic disorders, such as diabetes and metabolic syndrome. Monitoring 3-PGA levels helps to understand the metabolic dysregulation in these diseases. By analyzing 3-PGA and related metabolites, it is possible to assess cellular energy metabolism under different conditions, especially in response to hypoxia, exercise, or metabolic stress.
Figure 1. The Structure of 3-Phosphoglyceric Acid
The detection of 3-PGA is typically conducted using high-performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS), which are highly sensitive analytical techniques. MtoZ Biolabs offers a specialized 3-Phosphoglyceric Acid Analysis Service, supported by our advanced LC-MS platform and a team of metabolomics experts. Our service offers a comprehensive analysis of 3-phosphoglyceric acid, ensuring high sensitivity and precision.
Analysis Workflow
Service Advantages
1. High Sensitivity and Accuracy
MtoZ Biolabs' LC-MS analysis platform can detect extremely low concentrations of 3-phosphoglyceric acid and its metabolites, which is particularly important for studying their minute changes in cells, tissues, and bodily fluids.
2. High Specificity
By optimizing chromatographic separation conditions and mass spectrometry detection parameters, 3-phosphoglyceric acid and its various metabolites can be effectively distinguished in complex biological samples, minimizing interference from other endogenous or exogenous substances and improving detection specificity.
3. Customized Analysis
Tailored analytical solutions can be designed according to research needs, providing personalized solutions for different biological samples and target molecules.
Applications
1. Identification of metabolic pathway disturbances
2. Detection of disease biomarkers
3. Improvement of disease diagnosis
4. Acceleration in the discovery of novel therapeutics
5. Unveiling new insights into disease mechanisms
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. More than 3 materials under the same conditions must be selected for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 3-Phosphoglyceric Acid
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to offering the highest level of precision and accuracy through our 3-Phosphoglyceric Acid Analysis Service. We aim to facilitate your research and product development by providing accurate and reliable results with quick turnaround times.
How to order?
