3-Oxocholic Acid Analysis Service

3-Oxocholic acid (3-oxo-CA) is an oxidized bile acid metabolite derived from primary bile acids like cholic acid, formed through liver oxidation or by intestinal microbiota. Its distinctive 3-oxo group gives 3-oxo-CA unique chemical properties and biological functions, setting it apart from other bile acids. Research suggests that 3-oxo-CA plays a significant role in bile acid metabolism and is linked to liver health, gut function, and cholesterol metabolism disorders. Accurate measurement of 3-oxo-CA levels and its metabolic changes is crucial for understanding its role in both health and disease.

 

Figure 1. Molecular Structure of 3-Oxocholic Acid

 

MtoZ Biolabs offers 3-Oxocholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in 3-oxo-CA detection.

 

Analysis Workflow

 



 

Service Advantages

• Rapid Analysis Cycle and Cost-Effectiveness
• Stable, Reliable, and Highly Sensitive Results
• Comprehensive One-Stop Service for Extensive Testing Needs
• User-Friendly Operation with Wide Application Scope
• Supported by Extensive Bioanalytical Resources and Advanced Platforms

 

Sample Submission Requirements

Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

 

Applications

• Investigate 3-oxo-CA's role in bile acid pathways and explore its biological functions in health and disease.
• Assess 3-oxo-CA's metabolic changes in liver diseases and explore its potential role in liver function assessment.
• Study the impact of 3-oxo-CA on cholesterol metabolism, offering data support for related metabolic disease research.
• Explore interactions between 3-oxo-CA and gut microbiota, investigating its role in maintaining gut health.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 3-Oxocholic Acid

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into 3-oxo-CA 's extensive physiological roles through top-tier analytical techniques and expert services.