3-Nitro-L-Tyrosine Analysis Service
- Extensive expertise in handling various biological samples and extracting metabolites.
- State-of-the-art mass spectrometry platforms.
- Strict quality control to ensure reliable results.
- Comprehensive statistical and bioinformatics analysis.
- Personalized service to meet various research needs.
- Identifying new disease biomarkers
- Improving disease diagnosis
- Accelerating the discovery of novel therapeutics
- Providing new insights into disease mechanisms
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
3-Nitro-L-tyrosine is an amino acid derivative with a chemical structure composed of the amino acid tyrosine, where a nitro group (-NO₂) is attached to the third carbon of the aromatic ring. The chemical formula of 3-nitro-L-tyrosine is C₉H₁₀N₂O₅. This modification occurs through the nitration of the tyrosine residue, which can take place under oxidative stress conditions in biological systems. 3-Nitro-L-tyrosine has been recognized for its diverse biological activities and plays a significant role in various physiological and pathological processes. It is often associated with nitrosative stress and can serve as a marker for oxidative damage in tissues. Elevated levels of 3-nitro-L-tyrosine have been linked to inflammation, neurodegenerative diseases, cardiovascular disorders, and cancer, reflecting its involvement in cellular damage and disease progression. Moreover, 3-nitro-L-tyrosine can inhibit the activity of certain enzymes, especially those involved in cellular signaling and energy metabolism. This inhibition can disrupt normal cellular function, contributing to the pathogenesis of metabolic disorders and other diseases. By analyzing the metabolic pathways and products of 3-nitro-L-tyrosine under different physiological and pathological conditions, researchers can gain insights into its role in oxidative stress response, energy metabolism, and protein modification.
The levels of 3-nitro-L-tyrosine and its metabolites may also serve as valuable biomarkers for oxidative stress-related diseases. Monitoring changes in its concentration can help predict disease progression, assess the effectiveness of therapeutic interventions, and provide early indications for disease diagnosis. At MtoZ Biolabs, we are proud to offer an unparalleled 3-nitro-L-tyrosine Analysis Service, made possible by our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and our expert team of metabolomics professionals. Our service provides a comprehensive analysis of 3-nitro-L-tyrosine to solve your research problems with high sensitivity and accuracy .
Figure 1. The Structure of 3-Nitro-L-Tyrosine
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 3-Nitro-L-Tyrosine
4. Raw Data
5. Custom Analysis Report
With our 3-nitro-L-tyrosine analysis service, we aim to support your research and product development processes by delivering accurate and reliable results.
How to order?
