3-methyluridine Analysis Service

3-Methyluridine is a modified nucleoside that is found in the ribosomal RNA of several species, including bacteria, yeast, and mammals. It is a methylated form of uridine, where a methyl group is attached to the uracil base at the 3-position. This modification, which is believed to enhance the stability of the rRNA and improve the efficiency of protein synthesis, is catalyzed by specific enzymes known as methyltransferases. Given its potential roles in RNA stability and protein translation, 3-methyluridine has emerged as a subject of interest in biomedical research. Furthermore, changes in the levels of 3-methyluridine have also been linked to several diseases, including cancer and neurodegenerative disorders, making it a potentially valuable diagnostic marker or therapeutic target.

Figure 1. The Structure of 3-methyluridine

At MtoZ Biolabs, we are committed to providing you with the most reliable and accurate 3-methyluridine analysis service. We use high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), an advanced technique known for its high sensitivity and accuracy, for the analysis of 3-methyluridine. With our state-of-the-art technology and team of experienced scientists, we can help you overcome your research challenges and achieve your scientific objectives. 

Analysis Workflow

Service Advantages

• High accuracy and reproducibility
• Wide range of sample compatibility
• Comprehensive report with detailed analysis and expert interpretation
• Rapid turnaround time

Applications

Our 3-methyluridine analysis service can be applied in various research fields, including but not limited to:

• RNA modification studies
• Disease biomarker discovery
• Drug metabolism studies

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing

Note: Please provide details on sample collection and handling.

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 3-methyluridine

4. Raw Data

5. Custom Analysis Report

Contact us today to learn more about our services and how we can assist you in your research endeavors.