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    3-Methyladenine Analysis Service

      3-Methyladenine (3-MA) is a methylated derivative of adenine, an important purine nucleotide involved in the synthesis of DNA and RNA. Its chemical formula is C₆H₇N₅, and it has garnered attention due to its role in cellular signaling and metabolic pathways. 3-Methyladenine can be synthesized through methylation reactions involving S-adenosylmethionine (SAM) as the methyl donor. It can also be generated from the metabolic degradation of adenine under specific conditions. In vivo, it participates in various cellular signaling pathways, including those related to cell growth and apoptosis. Analyzing the levels of 3-methyladenine and its metabolites can serve as biomarkers for disease states, particularly in tumors and neurodegenerative diseases, providing a basis for early diagnosis and prognostic assessment. As an autophagy inhibitor, the analysis of 3-methyladenine and its metabolites helps to understand the role of autophagy in physiological and pathological processes, facilitating in-depth research into autophagy mechanisms.

       

      1838445498265620480-TheStructureof3-Methyladenine.png

      Figure 1. The Structure of 3-Methyladenine

       

      MtoZ Biolabs provides the state-of-the-art 3-Methyladenine Analysis Service, supported by our advanced liquid chromatography-mass spectrometry (LC-MS) platform and proficient metabolomics team. Our service provides a comprehensive 3-methyladenine analysis, aiding in the study of this important compound, catalyzing new discoveries in the fields of biology and medicine.

       

      Analysis Workflow

       

      1838445548983144448-Workflowof3-MethyladenineAnalysisService.PNG

       

      Service Advantages

      • Extensive experience in various biological sample preparation techniques
      • Professional standard operating procedure
      • State-of-the-art facilities and equipment for precise analysis
      • Expert team with extensive experience in metabolomics
      • Comprehensive data analysis
      • Excellent customer service and after-service support

       

      Applications

      • Identifying new disease biomarkers
      • Improving disease diagnosis
      • Accelerating the discovery of novel therapeutics
      • Providing new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample. 

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Store at -80°C to maintain stability.

       

      Note: Provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 3-Methyladenine

      4. Raw Data

      5. Custom Analysis Report

       

      Our 3-methyladenine analysis service aims to facilitate your research and product development processes by providing accurate and dependable results. Trust MtoZ Biolabs for your 3-methyladenine analysis needs.

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