3-β-Deoxycholic Acid Analysis Service

3-β-Deoxycholic acid is a secondary bile acid derived from cholesterol through the action of intestinal microorganisms. Its molecular formula is C₂₄H₄₀O₄, and its molecular weight is 392.57 g/mol. The compound's structure is characterized by a steroid nucleus with a hydroxyl group (-OH) at the 3rd position and a carboxylic acid group (-COOH) at the terminal end. Due to its microbial origin, the levels of 3-β-deoxycholic acid can serve as a biomarker for the composition and health of the gut microbiota. Abnormal levels may indicate disturbances in bile acid metabolism, which are associated with various diseases, such as inflammatory bowel disease (IBD), non-alcoholic fatty liver disease (NAFLD), and cholestasis. 

 



Figure 1. The Structure of 3-β-Deoxycholic Acid

 

MtoZ Biolabs provides an exceptional 3-β-Deoxycholic Acid Analysis Service, supported by our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and experienced metabolomics team. We deliver a comprehensive 3-β-deoxycholic acid analysis, aiding in developing targeted therapies to modulate the bile acid pool for treating metabolic disorders, gastrointestinal diseases, and even certain cancers..

 

Analysis Workflow 

 



 

Service Advantages

1. Continuously optimized experimental protocols and advanced instrument

 

2. Professional experimental design

 

3. Rapid turnaround time

 

4. High accuracy, specificity, and sensitivity

 

Applications

• Qualitative and quantitative analysis of 3-β-deoxycholic acid
• Identification of metabolites of the 3-β-deoxycholic acid
• Insight into the pharmacology of 3-β-deoxycholic acid

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample. 

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Sample Preservation

Store at -80°C to maintain stability.

 

Note: Provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 3-β-Deoxycholic Acid

4. Raw Data

5. Custom Analysis Report

 

By utilizing our 3-β-Deoxycholic Acid Analysis Service, we aim to facilitate your research and product development processes by delivering accurate and reliable results.