3-Aminoisobutanoic Acid Analysis Service

    3-Aminoisobutanoic Acid ( (also known as β-aminoisobutyric acid or BAIBA)) is an important non-protein amino acid synthesized in the body through metabolic pathways. BAIBA is generated through the action of adenylate deaminase in the creatine metabolism pathway and is involved in various biological processes such as muscle metabolism, insulin signaling, and lipid metabolism. Changes in its levels are closely associated with metabolic syndrome, diabetes, and obesity. Therefore, accurate analysis of BAIBA content and metabolism is essential for understanding its mechanisms in the body and its potential applications in disease.

     

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    Figure 1. Molecular Structure of 3-Aminoisobutanoic Acid

     

    MtoZ Biolabs offers 3-Aminoisobutanoic Acid Analysis Service using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of BAIBA in complex biological matrices.

     

    Analysis Workflow

     

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    Experimental Instruments

    • Liquid Chromatography-Mass Spectrometry (LC-MS)
    • Gas Chromatography-Mass Spectrometry (GC-MS)
    • Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

     

    Service Advantages

    • Rapid Analysis Cycle and Cost-Effectiveness
    • Stable, Reliable, and Highly Sensitive Results
    • Comprehensive One-Stop Service for Extensive Testing Needs
    • User-Friendly Operation with Wide Application Scope
    • Supported by Extensive Bioanalytical Resources and Advanced Platforms

     

    Sample Submission Requirements

    Sample Types

    Serum, plasma, urine, tissue homogenates, and other biological samples.

     

    Sample Volume

    At least 200 μL of liquid sample or 200 mg of tissue sample.

     

    Sample Preservation

    Store and transport samples at -80 °C to maintain BAIBA stability.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on BAIBA and Their Metabolites

    4. Raw Data

    5. Custom Analysis Report

     

    MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into BAIBA's extensive physiological roles through top-tier analytical techniques and expert services.

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