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    3,4-Dihydroxyphenylacetic Acid Analysis Service

      3,4-Dihydroxyphenylacetic acid (DOPAC) is a significant catecholamine metabolite and a key intermediate in dopamine metabolism. Changes in DOPAC levels reflect neurotransmitter metabolic states, making it crucial for neuroscience research, psychiatric studies, and the diagnosis and monitoring of neurodegenerative diseases. Abnormal DOPAC levels are linked to neurological disorders like Parkinson's disease, depression, and schizophrenia. Therefore, accurately detecting and quantifying DOPAC in biological samples is vital for understanding nervous system functions and pathology.

       1820738969865408512-MolecularStructureof3,4-DihydroxyphenylaceticAcid.png

      Figure 1. Molecular Structure of 3,4-Dihydroxyphenylacetic Acid

       

      MtoZ Biolabs offers 3,4-Dihydroxyphenylacetic Acid Analysis Service using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). This advanced method combines the separation capabilities of UPLC with the detection power of MS, ensuring high sensitivity and specificity in DOPAC detection.

       

      Analysis Workflow

       

      1820739083304554496-TheWorkflowof3,4-DihydroxyphenylaceticAcidAnalysis.png

       

      Service Advantages

      1. High Sensitivity and Precision

      UPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of DOPAC.

       

      2. Rapid and Efficient

      Optimized sample preparation and fast analysis ensure quick and efficient processing.

       

      3. Wide Applicability

      Suitable for various biological samples, including blood, urine, and tissues.

       

      4. Accurate and Reliable Data

      Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

       

      Sample Submission Requirements

      Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

       

      Applications

      • Monitor DOPAC levels to study neurotransmitter metabolism and nervous system functions.
      • Analyze DOPAC level changes in mental disorders such as depression and schizophrenia, aiding in disease diagnosis and treatment.
      • Detect DOPAC levels in patients with Parkinson's disease and other neurodegenerative disorders to evaluate disease progression and treatment efficacy.
      • Assess the impact of drugs on dopamine metabolism, supporting the development and efficacy evaluation of neurological drugs.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 3,4-Dihydroxyphenylacetic Acid

      4. Raw Data

      5. Custom Analysis Report

       

      Our 3,4-Dihydroxyphenylacetic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.

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