2-thiocytidine Analysis Service
- Expert team: A team of experienced analysts proficient in nucleoside analysis.
- Advanced techniques: State-of-the-art HPLC-MS/MS techniques ensure the accuracy and reliability of the results.
- Comprehensive report: A comprehensive report includes a detailed analysis of the results with relevant interpretations.
- Excellent customer service: Provides excellent pre- and post-analysis support.
- Biomarker discovery
- Disease diagnosis
- Drug development
- Mechanistic studies of tRNA modifications
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
2-thiocytidine is a modified nucleoside where the oxygen atom at the 2-position of the cytidine base is replaced with sulfur. While commonly associated with transfer RNA (tRNA) modifications, this nucleoside has gained attention for its significant anticancer properties. As a purine nucleoside analog, 2-thiocytidine exhibits broad antitumor activity, particularly targeting indolent lymphoid malignancies. It exerts its anticancer effects by inhibiting DNA synthesis, ultimately inducing apoptosis in cancer cells. This makes 2-thiocytidine a promising candidate in cancer therapeutics, especially for malignancies that are resistant to conventional treatments.
In addition to its therapeutic potential, 2-thiocytidine plays a vital role in maintaining the stability and function of tRNA. This sulfur modification enhances the stability of tRNA molecules and helps ensure accurate protein synthesis by improving codon recognition, particularly under stress conditions. The dual role of 2-thiocytidine in both therapeutic applications and essential cellular processes highlights its importance in biochemical and clinical research.
Figure 1. The Structure of 2-thiocytidine
At MtoZ Biolabs, we provide comprehensive 2-thiocytidine analysis services. Our proprietary techniques, combined with our advanced HPLC-MS/MS platforms, allow us to deliver accurate, sensitive, and reliable 2-thiocytidine analysis. We can assist researchers in detecting and quantifying 2-thiocytidine in various biological samples, thereby facilitating their research in nucleoside modifications.
Analysis Workflow
Service Advantages
Applications
The 2-thiocytidine analysis service can be used in a variety of research fields, including but not limited to:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 2-thiocytidine
4. Raw Data
5. Custom Analysis Report
Through our 2-thiocytidine analysis service, we aim to facilitate your research by providing accurate and reliable results. If you would like to inquire about our services, please feel free to contact us.
How to order?
