2-Oxoadipic Acid Analysis Service

    2-Oxoadipic Acid, also known as α-ketoadipic acid, is a dicarboxylic acid with the chemical formula C₆H₈O₄. It features two carboxyl groups and a keto group, making it a significant intermediate in various metabolic pathways. 2-Oxoadipic Acid plays a pivotal role in the lysine and tryptophan degradation pathways, serving as an intermediate in the catabolism of these essential amino acids. The metabolic pathway involving 2-Oxoadipic Acid includes its conversion from 2-oxoglutarate through a series of enzymatic reactions involving specific enzymes like 2-oxoadipate dehydrogenase. This pathway is crucial for energy production and the synthesis of various biomolecules.

     

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    Figure 1. The Structure of 2-Oxoadipic Acid

     

    Recent research has highlighted the significance of 2-Oxoadipic Acid in several physiological and pathological processes. Elevated levels of 2-Oxoadipic Acid have been associated with metabolic disorders, including inherited diseases such as 2-oxoadipic aciduria. This condition, resulting from defects in the enzymes involved in the degradation of lysine and tryptophan, underscores the importance of 2-Oxoadipic Acid as a biomarker for metabolic dysfunction. The comprehensive analysis of 2-Oxoadipic Acid is essential for understanding its role in metabolic pathways, identifying disease states, and elucidating metabolic profiles. By examining its concentration and distribution in biological samples, researchers can gain insights into metabolic disorders and the efficacy of therapeutic interventions.

     

    MtoZ Biolabs utilizes advanced LC-MS/MS systems for metabolite quantification, providing a comprehensive view of the metabolite profile. Our experienced scientists offer personalized assistance, from experimental design to data analysis, ensuring reliable and reproducible results.

     

    Analysis Workflow 

     

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    Service Advantages

    • Advanced Technology: Latest LC-MS/MS systems for accurate quantification
    • Professional Team: Expert team with extensive experience in metabolomics
    • Customizable Design: Personalized experimental design to fit your research needs
    • Comprehensive Report: Detailed report with results and in-depth analysis

     

    Applications

    • Basic Biological Research
    • Disease Biomarker Discovery
    • Drug Metabolism Studies
    • Nutritional Research

     

    Sample Submission Requirements

     

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    • Samples should be stored at -80℃ and shipped with dry ice.
    • Other sample types, please contact us for more details.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on 2-Oxoadipic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    At MtoZ Biolabs, we are committed to providing high-quality and reliable 2-Oxoadipic Acid analysis service to facilitate your research. For more details, please feel free to contact us.

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