2'-O-methyluridine Analysis Service
- Extensive experience in various biological sample preparation techniques
- Professional standard operating procedure
- State-of-the-art facilities and equipment for precise analysis
- Expert team with extensive experience in metabolomics
- Comprehensive data analysis
- Excellent customer service and after-service support
- Biomarker discovery
- Disease diagnosis and prognosis
- Drug response prediction
- Basic biological research
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
2'-O-methyluridine is a modified nucleoside in which a methyl group is added to the hydroxyl group at the 2' position of the ribose sugar in uridine. This structural modification is significant in the regulation of RNA function and stability. 2'-O-methylation is a common post-transcriptional modification found in various types of RNA, including transfer RNA (tRNA), ribosomal RNA (rRNA), and messenger RNA (mRNA). The presence of 2'-O-methyluridine in RNA enhances the stability of RNA molecules by protecting them from degradation by nucleases, as well as influencing RNA folding and interactions with proteins.
In mRNA, 2'-O-methylation occurs as part of the 5' cap structure in eukaryotes, playing a key role in mRNA translation, stability, and regulation. Additionally, 2'-O-methyluridine modifications in tRNA and rRNA contribute to the proper functioning of the translation machinery, impacting the fidelity and efficiency of protein synthesis.
Figure 1. The Structure of 2'-O-methyluridine
MtoZ Biolabs offers a highly accurate and sensitive 2'-O-methyluridine Analysis Service using advanced mass spectrometry technologies. Our service is designed to support research in RNA biology, epigenetics, cancer biology, and virology by providing reliable quantification and profiling of 2'-O-methyluridine in various RNA types. This data is critical for understanding the role of RNA modifications in cellular processes and disease states.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Comprehensive Information on 2'-O-methyluridine
4. Raw Data
5. Custom Analysis Report
Feel free to contact us for more information about our 2'-O-methyluridine Analysis Service. Let MtoZ Biolabs be your partner in your research journey.
How to order?
