2'-O-methylinosine Analysis Service

    2'-O-methylinosine is a modified nucleoside found in the anticodon loop of tRNA. It is a product of the methylation of inosine, a process catalyzed by a tRNA 2'-O-methyltransferase. The introduction of the 2'-O-methyl group enhances the stability of tRNA and improves the accuracy and efficiency of protein synthesis. Abnormalities in 2'-O-methylinosine levels may be associated with certain diseases, including cancer and neurological disorders. Therefore, understanding 2'-O-methylinosine and its methylation process can provide valuable insights into the regulation of gene expression and disease pathogenesis.

     

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    Figure 1. The Structure of 2'-O-methylinosine

     

    At MtoZ Biolabs, we have developed a comprehensive 2'-O-methylinosine analysis service, designed to provide our clients with the most accurate and detailed data. Our team of experienced scientists and cutting-edge technologies allow us to deliver reliable data with great accuracy and precision.

     

    Analysis Workflow

     

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    Service Advantages 

    • Extensive expertise in handling various biological samples and extracting metabolites.
    • State-of-the-art mass spectrometry platforms. 
    • Strict quality control to ensure reliable results.
    • Comprehensive bioinformatics analysis.
    • Personalized service to meet various research needs.

     

    Applications

    • Gene expression regulation
    • Disease pathogenesis
    • Drug development
    • Biomarker discovery

     

    Sample Submission Requirements

    1. Sample Types

    Serum, plasma, urine, tissues, and other biological samples.

     

    2. Sample Volume

    • Animal tissue ≥ 100 mg
    • Plant tissue ≥ 200 mg
    • Serum/ Plasma ≥ 200 μL
    • Urine ≥ 2 mL

     

    3. Storage and Shipping

    Samples should be stored at -80℃ and shipped with dry ice.

     

    Note: Please provide details on sample collection and handling.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Comprehensive Information on 2'-O-methylinosine

    4. Raw Data

    5. Custom Analysis Report

     

    For more information, please contact our customer service. We look forward to supporting your research with our professional and high-quality 2'-O-methylinosine analysis service.

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