2'-O-methylinosine Analysis Service

2'-O-methylinosine is a modified nucleoside found in the anticodon loop of tRNA. It is a product of the methylation of inosine, a process catalyzed by a tRNA 2'-O-methyltransferase. The introduction of the 2'-O-methyl group enhances the stability of tRNA and improves the accuracy and efficiency of protein synthesis. Abnormalities in 2'-O-methylinosine levels may be associated with certain diseases, including cancer and neurological disorders. Therefore, understanding 2'-O-methylinosine and its methylation process can provide valuable insights into the regulation of gene expression and disease pathogenesis.

Figure 1. The Structure of 2'-O-methylinosine

At MtoZ Biolabs, we have developed a comprehensive 2'-O-methylinosine analysis service, designed to provide our clients with the most accurate and detailed data. Our team of experienced scientists and cutting-edge technologies allow us to deliver reliable data with great accuracy and precision.

Analysis Workflow

Service Advantages 

• Extensive expertise in handling various biological samples and extracting metabolites.
• State-of-the-art mass spectrometry platforms. 
• Strict quality control to ensure reliable results.
• Comprehensive bioinformatics analysis.
• Personalized service to meet various research needs.

Applications

• Gene expression regulation
• Disease pathogenesis
• Drug development
• Biomarker discovery

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples.

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

3. Storage and Shipping

Samples should be stored at -80℃ and shipped with dry ice.

Note: Please provide details on sample collection and handling.

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Comprehensive Information on 2'-O-methylinosine

4. Raw Data

5. Custom Analysis Report

For more information, please contact our customer service. We look forward to supporting your research with our professional and high-quality 2'-O-methylinosine analysis service.