2-Hydroxyestrone Analysis Service
- Predicting breast cancer risk
- Studying hormone metabolism
- Developing innovative therapeutics
- Investigating mechanisms of hormone-related diseases
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
2-Hydroxyestrone (2-OHE1) is a key metabolite in estrogen metabolism, formed through the hydroxylation of estrone at the C2 position. Structurally, 2-OHE1 features a hydroxyl group at the C2 position, which gives it distinct biological activity compared to other estrogen metabolites. In contrast to 16α-Hydroxyestrone, 2-OHE1 is considered to have weaker estrogenic activity and may even exhibit anti-estrogenic effects. Its levels in the body are typically associated with a lower risk of hormone-dependent cancers such as breast and endometrial cancer, making it a significant focus in disease prevention research. One major research area for 2-OHE1 is its role in balancing estrogen metabolism. Studies suggest that the ratio between 2-OHE1 and other hydroxyestrones may be a crucial factor in predicting cancer risk, particularly in the context of breast cancer. The metabolic pathway of 2-OHE1 involves various enzymes, and changes in its levels may be closely related to genetic polymorphisms, environmental exposures, and endocrine-disrupting factors. Quantitative analysis of 2-OHE1 is invaluable for precision medicine, disease risk assessment, and the development of personalized treatment strategies. Through highly sensitive mass spectrometry techniques, researchers can accurately measure 2-OHE1 concentrations and track its dynamic changes in different pathological conditions, providing strong support for clinical research.
Figure 1. The Structure of 2-Hydroxyestrone
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, providing advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of 2-hydroxyestrone. We ensure the accuracy of the quantification of 2-hydroxyestrone and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you are interested in our 2-hydroxyestrone analysis service, please feel free to contact us at any time, and we will be fully committed to providing you with high-quality analytical services and technical support.
Analysis Workflow
Service Advantages
1. Advance Analysis Platform: MtoZ Biolabs established an advanced 2-hydroxyestrone analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all 2-hydroxyestrone analysis data, delivering clients a detailed and comprehensive data report.
4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details （Materials, Instruments and Methods,etc.）
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 2-Hydroxyestrone Analysis
4. Raw Data
5. Custom Analysis Report
Through our 2-hydroxyestrone analysis service, we aim to facilitate your research and product development processes by providing accurate and reliable results.
How to order?
